Results 101 to 110 of about 466,412 (376)

Real‐world clinical experience with serum MOG and AQP4 antibody testing by live versus fixed cell‐based assay

Annals of Clinical and Translational Neurology, Volume 12, Issue 3, Page 556-564, March 2025.
Abstract Objective To assess the real‐world performance of a live (LCBA) versus a fixed (FCBA) cell‐based assay for the detection of serum antibodies directed against myelin oligodendrocyte glycoprotein (MOG‐IgG) and aquaporin‐4 (AQP4‐IgG). Methods This was a retrospective study of patients evaluated at a single tertiary academic referral center, with ...
Yana Said, Angeliki Filippatou, Conlan Tran, LuAnn Rezavi, Kai Guo, Matthew D. Smith, Yasmin Resto, John J. Chen, Peter A. Calabresi, Patrizio Caturegli, Sean J. Pittock, Eoin P. Flanagan, Elias S. Sotirchos   +12 more
wiley   +1 more source

Preliminary Results of the FASM Study, an On-Going Italian Active Pharmacovigilance Project

Pharmaceuticals, 2020
Background and aim: Disease-modifying therapies (DMTs) used in multiple sclerosis (MS) have distinct safety profiles. In this paper, we report preliminary results of an on-going pharmacovigilance project (the FASM study). Results: Neurologists working at
Giorgia Teresa Maniscalco, Vincenzo Brescia Morra, Ciro Florio, Giacomo Lus, Gioacchino Tedeschi, Maddalena Cianfrani, Renato Docimo, Stefania Miniello, Felice Romano, Leonardo Sinisi, Daniele L. A. Spitaleri, Giuseppe Longo, Ugo Trama, Maria Triassi, FASM Group, Cristina Scavone, Annalisa Capuano   +16 more
doaj   +1 more source

Delayed P100-Like Latencies in Multiple Sclerosis: A Preliminary Investigation Using Visual Evoked Spread Spectrum Analysis. [PDF]

PLoS ONE, 2016
Conduction along the optic nerve is often slowed in multiple sclerosis (MS). This is typically assessed by measuring the latency of the P100 component of the Visual Evoked Potential (VEP) using electroencephalography.
Hanni S M Kiiski, Sinéad Ní Riada, Edmund C Lalor, Nuno R Gonçalves, Hugh Nolan, Robert Whelan, Róisín Lonergan, Siobhán Kelly, Marie Claire O'Brien, Katie Kinsella, Jessica Bramham, Teresa Burke, Seán Ó Donnchadha, Michael Hutchinson, Niall Tubridy, Richard B Reilly   +15 more
doaj   +1 more source

Correlation of multiple sclerosis incidence in the UK 1990-2010 with geomagnetic disturbances [PDF]

arXiv, 2013
Recently, Mackenzie et al. reported incidence and prevalence of multiple sclerosis (MS) in the UK from 1990-2010. Authors of this report indicated that they could not explain the cause of decreasing MS incidence trend in the UK during this time period.
arxiv  

Ethnoracial disparities in gray matter atrophy are mediated by structural disconnectivity in multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 12, Issue 3, Page 615-630, March 2025.
This study aimed to assess gray matter (GM) atrophy, the contribution of white matter (WM) lesions, and consequent structural disconnectivity in minority patients with multiple sclerosis (PwMS). Minority PwMS were found to have greater lesion burden and GM atrophy. Differences in GM atrophy were partially mediated by WM pathology. Abstract Objective To
Ahmed Bayoumi, Joseph A. Thomas, Breanna R. Alonzo, Juan Jimenez, Christopher M. Orlando, Carlos A. Pérez, Khader M. Hasan, Jerry S. Wolinsky, John A. Lincoln   +8 more
wiley   +1 more source

Enhancing patients’ role in scientific writing: insights from a global participatory approach with people with multiple sclerosis

Research Involvement and Engagement
Introduction This study aims to describe a participatory process by investigating the perceptions and expectations of people with multiple sclerosis (pwMS) toward the scientific writing (SW) process and the role of patient engagement and quality of life ...
Mariarosaria Savarese, Dilara Usta, Federico Bozzoli, Vanessa Fanning, Federica Molinari, Guendalina Graffigna, Paola Zaratin   +6 more
doaj   +1 more source

Multiple Sclerosis Lesion Segmentation -- A Survey of Supervised CNN-Based Methods [PDF]

arXiv, 2020
Lesion segmentation is a core task for quantitative analysis of MRI scans of Multiple Sclerosis patients. The recent success of deep learning techniques in a variety of medical image analysis applications has renewed community interest in this challenging problem and led to a burst of activity for new algorithm development.
arxiv  

Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS

Neuropathology and Applied Neurobiology, 2000
Several processes take place during an attack of demyelination in multiple sclerosis (MS). The timing of these various processes, and thus of the attack in its entirety, is important if therapeutic stratagies are to be planned. Attempts have been made to introduce and investigate variables relevant to timing the disease processes, leading to staging ...
van der Valk, P., de Groot, C.J.
openaire   +4 more sources

Progressive Myoclonus Epilepsy: Distinctive MRI Changes in Cerebellar and Motor Networks

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive myoclonus epilepsy (PME) is a rare generalized epilepsy syndrome with a well‐characterized genetic basis. The brain networks that are affected to give rise to the distinctive symptoms of PME are less well understood. Methods Eleven individuals with PME with a confirmed genetic diagnosis and 22 controls were studied.
Jillian M. Cameron, Remika Mito, Samuel F. Berkovic, Graeme D. Jackson   +3 more
wiley   +1 more source

Autoimmunity to a ribonucleoprotein drives neuron loss in multiple sclerosis models

Neurobiology of Disease, 2022
Neurodegeneration, the progressive loss or damage to neurons and axons, underlies permanent disability in multiple sclerosis (MS); yet its mechanisms are incompletely understood.
Cole D. Libner, Hannah E. Salapa, Catherine Hutchinson, Todd E. Stang, Patricia A. Thibault, S. Austin Hammond, Michael C. Levin   +6 more
doaj