Results 81 to 90 of about 466,412 (376)

Assessment of concurrent neoplasms and a paraneoplastic association in MOGAD

Annals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 861-870, April 2025.
Abstract Cases of myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD) co‐occurring with neoplasms have been reported. In this international, retrospective cohort study in South Korea and the USA, 16 of 445 (3.6%) patients with MOGAD had concurrent neoplasm within 2 years of MOGAD onset, resulting in a standardized incidence ...
Young Nam Kwon, Nanthaya Tisavipat, Yong Guo, Stephanie B. Syc‐Mazurek, Ji Yeon Han, Jun‐Soon Kim, Kyomin Choi, Seong‐il Oh, Seok‐Jin Choi, Eunhee Sohn, Jeeyoung Oh, Seung Woo Kim, Ha Young Shin, Byung Chan Lim, Byoung Joon Kim, Kyung Seok Park, Jung‐Joon Sung, Se Hoon Kim, Sung‐Hye Park, Anastasia Zekeridou, Claudia F. Lucchinetti, Sean J. Pittock, John J. Chen, Eoin P. Flanagan, Sung‐Min Kim   +24 more
wiley   +1 more source

Anti-SARS-CoV-2 vaccination in people with multiple sclerosis: Lessons learnt a year in

Frontiers in Immunology, 2022
It has been over a year since people with multiple sclerosis (pwMS) have been receiving vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With a negligible number of cases in which vaccination led to a relapse or new onset MS,
Maura Pugliatti, Maura Pugliatti, Hans-Peter Hartung, Hans-Peter Hartung, Hans-Peter Hartung, Celia Oreja-Guevara, Celia Oreja-Guevara, Carlo Pozzilli, Laura Airas, Laura Airas, Mona Alkhawajah, Mona Alkhawajah, Nikolaos Grigoriadis, Melinda Magyari, Bart Van Wijmeersch, Bart Van Wijmeersch, Bart Van Wijmeersch, Magd Zakaria, Ralf Linker, Andrew Chan, Patrick Vermersch, Thomas Berger, Thomas Berger   +22 more
doaj   +1 more source

Towards an accurate and generalizable multiple sclerosis lesion segmentation model using self-ensembled lesion fusion [PDF]

arXiv, 2023
Automatic multiple sclerosis (MS) lesion segmentation using multi-contrast magnetic resonance (MR) images provides improved efficiency and reproducibility compared to manual delineation. Current state-of-the-art automatic MS lesion segmentation methods utilize modified U-Net-like architectures.
arxiv  

Explaining temporal trends in annualized relapse rates in placebo groups of randomized controlled trials in relapsing multiple sclerosis: systematic review and meta-regression [PDF]

Multiple Sclerosis Journal, 19(12):1580-1586, 2013, 2013
Background: Recent studies have shown a decrease in annualised relapse rates (ARRs) in placebo groups of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS). Methods: We conducted a systematic literature search of RCTs in RMS.
arxiv   +1 more source

Emotional and Behavioral Encounters of Children with Parental Multiple Sclerosis [PDF]

, 2017
Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system and is prevalent among adults who have school-age children. Persons diagnosed with MS often experience physical and psychological disabilities that are likely to affect the ...
Dambo, Neffisatu, Farquharson, Garcia
core  

CSF cytokine, chemokine and injury biomarker profile of glial fibrillary acidic protein (GFAP) autoimmunity

Annals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 855-860, April 2025.
Abstract Defining the CSF cytokine/chemokine and injury biomarker signature of glial fibrillary acidic protein (GFAP) autoimmunity can inform immunopathogenesis. CSF GFAP‐IgG‐positive samples (N = 98) were tested for 17 cytokines/chemokines, neurofilament light chain (NfL), and GFAP (ELLA, Bio‐Techne).
Yahel Segal, Georgios Mangioris, Vanda Lennon, Binxia Yang, Divyanshu Dubey, Eoin P. Flanagan, Andrew McKeon, John R. Mills, Michel Toledano, Ivana Vodopivec, Sean J. Pittock, Anastasia Zekeridou   +11 more
wiley   +1 more source

Amiloride, fluoxetine or riluzole to reduce brain volume loss in secondary progressive multiple sclerosis: the MS-SMART four-arm RCT

Efficacy and Mechanism Evaluation, 2020
Background: Neuroprotective drugs are needed to slow or prevent neurodegeneration and disability accrual in secondary progressive multiple sclerosis.
Floriana De Angelis, Peter Connick, Richard A Parker, Domenico Plantone, Anisha Doshi, Nevin John, Jonathan Stutters, David MacManus, Ferran Prados, Ian Marshall, Bhavana Solanky, Rebecca S Samson, Frederik Barkhof, Sebastien Ourselin, Marie Braisher, Moira Ross, Gina Cranswick, Sue H Pavitt, Sharmilee Gnanapavan, Gavin Giovannoni, Claudia AM Gandini Wheeler-Kingshott, Clive Hawkins, Basil Sharrack, Roger Bastow, Christopher J Weir, Nigel Stallard, Siddharthan Chandran, Jeremy Chataway   +27 more
doaj   +1 more source

Multiple Sclerosis Lesion Analysis in Brain Magnetic Resonance Images: Techniques and Clinical Applications [PDF]

arXiv, 2021
Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual patient's neurological symptoms and signs.
arxiv  

A systematic review and meta-analyses of pregnancy and fetal outcomes in women with multiple sclerosis: a contribution from the IMI2 ConcePTION project. [PDF]

, 2020
Neurologists managing women with Multiple Sclerosis (MS) need information about the safety of disease modifying drugs (DMDs) during pregnancy. However, this knowledge is limited.
A Haghikia, AL Nguyen, C Weber-Schoendorfer, D Moher, E Lu, E Lu, E Portaccio, G Comi, HV De Las, J Thone, JP Higgins, L Shamseer, MK Houtchens, N Ebrahimi, PK Coyle, R Alroughani, R Boskovic, S Herbstritt, S Pernia, S Thiel, SC MacDonald   +20 more
core   +1 more source

Social cognition in pediatric-onset multiple sclerosis (MS) [PDF]

Multiple Sclerosis Journal, 2014
Background: Pediatric-onset multiple sclerosis (MS) patients represent a subpopulation who are diagnosed during the course of development. Social cognitive deficits have recently been recognized in adults with MS. It is critical to identify whether these youngest patients with the disorder are also at risk.
Re Cleary, Le Charvet, Anita Belman, Katherine Vazquez, Lb Krupp   +4 more
openaire   +3 more sources