Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
MSA Class Logos: a web server for automated sequence logo generation for user-defined sequence classes based on one multiple sequence alignment. [PDF]
González-Reyes MF +3 more
europepmc +1 more source
Component-Based Design and Assembly of Heuristic Multiple Sequence Alignment Algorithms. [PDF]
Shi H, Zhang X.
europepmc +1 more source
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
The Historical Evolution and Significance of Multiple Sequence Alignment in Molecular Structure and Function Prediction. [PDF]
Zhang C +6 more
europepmc +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
TSTA: thread and SIMD-based trapezoidal pairwise/multiple sequence-alignment method. [PDF]
Zong P, Deng W, Liu J, Ruan J.
europepmc +1 more source
A Detailed View of KIR Haplotype Structures and Gene Families as Provided by a New Motif-Based Multiple Sequence Alignment. [PDF]
Roe D +6 more
europepmc +1 more source
FMAlign2: a novel fast multiple nucleotide sequence alignment method for ultralong datasets [PDF]
Pinglu Zhang +5 more
openalex +1 more source

