Results 231 to 240 of about 1,008,958 (324)

A Structurally-Validated Multiple Sequence Alignment of 497 Human Protein Kinase Domains. [PDF]

Sci Rep, 2019
Modi V, Dunbrack RL.
europepmc   +1 more source

MAUSA Software download for multiple sequence alignments [PDF]

, 2005
PJ Uren, R. M. Cameron-Jones, Ahj Sale
openalex  

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

DeepMSA: constructing deep multiple sequence alignment to improve contact prediction and fold-recognition for distant-homology proteins. [PDF]

Bioinformatics, 2020
Zhang C, Zheng W, Mortuza SM, Li Y, Zhang Y.   +4 more
europepmc   +1 more source

Development of advanced computational systems for multiple sequence alignments by using heterogeneous biological information

, 2014
Francisco Ortuño
openalex   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

DeepECA: an end-to-end learning framework for protein contact prediction from a multiple sequence alignment. [PDF]

BMC Bioinformatics, 2020
Fukuda H, Tomii K.
europepmc   +1 more source

A fast algorithm for the constrained multiple sequence alignment problem

, 2006
Dan He, Abdullah N. Arslan, Alan C. H. Ling   +2 more
openalex   +1 more source

Multiple sequence alignment by clustal W.

Adeeba Tabassum (21781882), Nadia Zeeshan (6093272), Amber Afroz (15447539)   +2 more
openalex   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source