Results 161 to 170 of about 478,489 (280)

Clinical, epidemiological, and genomic evidence on mpox in mainland China, 2022-2025: a scoping review. [PDF]

Front Microbiol
Peng Y, Geng Y, Yang F, Yang T.
europepmc   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Time Series Transformer for long-term CD4 trajectory prediction in HIV patients: a novel deep learning approach. [PDF]

Front Cell Infect Microbiol
Lu Q, Li T, Chen J, Ba H, Zhang Y, Li J, Yin J, Ma K, Liu H, Jin J.   +9 more
europepmc   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Thermodynamic and Structural Determinants of Ni(II), Co(II), and Zn(II) Binding to an XHXXHXH Peptide Motif. [PDF]

J Pept Sci
Honda K, Haneoka H, Suzuki T, Tamura A.
europepmc   +1 more source

Use of MRI-double inversion recovery sequence for early diagnosis of multiple sclerosis: case series

BMC Neurology
Zhu, Dan, Shao, Yongjia, Zhang, Nana, Wu, Zhourui, Cheng, Liming, Zhou, Hongyu, Chu, ShuGuang   +6 more
openaire   +2 more sources

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Labyrinthula merlionensis sp. nov.: A Novel Labyrinthulid Infecting Marine Diatoms. [PDF]

J Eukaryot Microbiol
Sim CWH, Walde M, Strindberg H, Kaur A, Le Panse S, Gourvil P, Jahren J, Vaulot D, Lopes Dos Santos A.   +8 more
europepmc   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

A deep learning-based score to evaluate multiple sequence alignments. [PDF]

Mol Biol Evol
Serok N, Polonsky K, Ashkenazy H, Mayrose I, Thorne JL, Pupko T.   +5 more
europepmc   +1 more source