Results 151 to 160 of about 453,835 (257)

ALS mutations disrupt self-association between the ubiquilin STI1 hydrophobic groove and internal placeholder sequences. [PDF]

EMBO J
Onwunma J, Binsabaan S, Allen SP, Thanthirige SR, Gaur D, Sankaran B, Wohlever ML.   +6 more
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Global distribution and evolution of human metapneumovirus A2b2 clade: Insights from genomic surveillance. [PDF]

Epidemiol Infect
Bucala MD, Brenner M.
europepmc   +1 more source

Use of MRI-double inversion recovery sequence for early diagnosis of multiple sclerosis: case series

BMC Neurology
Zhu, Dan, Shao, Yongjia, Zhang, Nana, Wu, Zhourui, Cheng, Liming, Zhou, Hongyu, Chu, ShuGuang   +6 more
openaire   +2 more sources

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

HERA: a Hybrid Euler Reservoir Architecture for multivariate time series classification. [PDF]

Sci Rep
Zhang S, Le W, Jia ZH, Wu H.
europepmc   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Linkage-aware inference of fitness from short-read time-series genomic data. [PDF]

Virus Evol
Abdullah SMU, Sohail MS, Louie RHY, Sun Y, Barton JP, McKay MR.   +5 more
europepmc   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Lipoid Pneumonia: HRCT and MRI Spectrum, Diagnostic Pitfalls, and Imaging-Based Diagnostic Workflow. [PDF]

Diagnostics (Basel)
Adorna M, Contino M, Libra A, Mauro LA, Castiglione DG, Mattina C, Mauceri C, Crimi C, Terminella A, Cusumano G, Gurrera A, Foti PV, Sambataro G, Basile A, Vancheri C, Palmucci S.   +15 more
europepmc   +1 more source