Results 171 to 180 of about 191,987 (285)

Temporal dynamics and functional annotation of transcriptome rhythmicity in HEK293T cells. [PDF]

open access: yesPLoS One
Sun Y   +8 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Neural circuits for decision-making based on pineal photoreception in zebrafish. [PDF]

open access: yesProc Natl Acad Sci U S A
Wada S   +5 more
europepmc   +1 more source

Multiple zeta functions :the double sine function and the signed double Poisson summation formula

open access: yesMultiple zeta functions :the double sine function and the signed double Poisson summation formula
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Linking gut microbiota rhythmicity to circadian maturation in infants. [PDF]

open access: yesSci Rep
Mühlematter C   +5 more
europepmc   +1 more source

Algebraic relations between special values of multiple sine functions

open access: yesAlgebraic relations between special values of multiple sine functions
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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