Results 141 to 150 of about 14,857,533 (356)
Multiplicity of solutions to the sum of polyharmonic equations with critical Sobolev exponents
Electronic Journal of Differential Equations, 2015 In this article, we prove multiplicity of solutions for the sum of polyharmonic equation with critical Sobolev exponent. The proof is based upon the methods of weakly lower semi-continuous of the functionals and the Mountain Pass Lemma without (PS ...
Wei Liu, Gao Jia, Lu-Quian Guo
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Suboptimal solutions to network team optimization problems
, 2009 Smoothness of the solutions to network team optimization problems with statistical information structure is investigated. Suboptimal solutions expressed as linear combinations of elements from sets of basis functions containing adjustable parameters are ...
Gnecco, Giorgio, Sanguineti, Marcello
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
, 2015 This report sets out how UK policy makers, local authorities, commissioners and frontline services can respond to the challenges faced by people experiencing multiple needs.
core
Critical points approaches for multiple solutions of a quasilinear periodic boundary value problem
Electronic Journal of Qualitative Theory of Differential EquationsOptimization problems are omnipresent in the mathematical modeling of real world systems and cover a very extensive range of applications becoming apparent in all branches of Economics, Finance, Materials Science, Astronomy, Physics, Structural and ...
Shapour Heidarkhani +3 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Electronic Journal of Differential Equations, 2004 We prove a critical-point result which provides conditions for the existence of infinitely many critical points of a strongly indefinite functional with perturbed symmetries.
Monica Clapp +2 more
doaj
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source