Results 81 to 90 of about 3,662,481 (292)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Natural convection in a cubical cavity: Case of multiple solutions [PDF]
, 2003 The purpose of this report is to study an interesting case of natural convection13; in a cubical cavity. A set of boundary conditions has been applied on the six walls and13; the buoyancy driven xB0;ow inside the cavity is due to the heating of the ...
Deshpande, MD
core
Steady-state solutions for Schrodinger equations in photonic lattice
Electronic Journal of Differential Equations, 2018 In this article, we study a nonlinear Schrodinger equation arising in optics. Firstly we prove the existence of multiple solutions of this equation. Secondly, we consider a nonlinear Schrodinger system which is intimately related to the Schrodinger ...
Wen-Long Li
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Using a genetic algorithm for optimizing the functional decomposition of multiple-valued functions [PDF]
, 1997 The genetic algorithm which determines the good functional decomposition of multiple-valued logic functions is presented. The algorithm expands the range of searching for a best decomposition, providing the optimal column multiplicity.
Kalganova, T, Kochergov, E, Strechen, N
core
How does framing influence preference for multiple solutions to societal problems? [PDF]
PLoS One, 2023 Wu JS, Kremen C, Zhao J.
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source