Results 81 to 90 of about 8,502,103 (299)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Existence of multiple solutions and estimates of extremal values for a Kirchhoff type problem with fast increasing weight and critical nonlinearity

open access: yesElectronic Journal of Differential Equations, 2018
In this article, we study the Kirchhoff type problem $$ -\Big(a+\epsilon\int_{\mathbb{R}^3} K(x)|\nabla u|^2dx\Big)\hbox{div} (K(x)\nabla u)=\lambda K(x)f(x)|u|^{q-2}u+K(x)|u|^{4}u, $$ where $x\in \mathbb{R}^3$, $10$.
Xiaotao Qian, Jianqing Chen
doaj  

Multiple positive solutions for a p-laplacian dirichlet problem with superdiffusive reaction

open access: yes, 2010
A parametric Dirichlet elliptic problem, driven by the p − Laplacian, and with a superdiffusive reaction is studied. First, it is shown that there exists a λ ∗> 0, such that for every parameter λ ≥ λ∗, the problem has a strictly positive smooth ...
Aizicovici, S   +5 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Combined effects of Choquard and singular nonlinearities in fractional Kirchhoff problems

open access: yesAdvances in Nonlinear Analysis, 2020
The aim of this paper is to study the existence and multiplicity of solutions for a class of fractional Kirchho problems involving Choquard type nonlinearity and singular nonlinearity.
Wang Fuliang, Hu Die, Xiang Mingqi
doaj   +1 more source

Migration and infectious disease in the etiology of multiple sclerosis: A case-control study

open access: yes, 1989
Epidemiological study on multiple sclerosis risk of migration from South to North ...
Altobelli A.   +2 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Multiplicity of solutions for a perturbed fractional Schrodinger equation involving oscillatory terms

open access: yesElectronic Journal of Differential Equations, 2018
In this article we study the perturbed fractional Schrodinger equation involving oscillatory terms $$\displaylines{ (-\Delta)^{\alpha} u+u =Q(x)\Big(f(u)+\epsilon g(u)\Big), \quad x\in \mathbb{R}^N\cr u\geq 0, }$$ where $\alpha\in (0, 1)$ and $N>
Chao Ji, Fei Fang
doaj  

Multiple solutions to a Dirichlet problem with p-Laplacian and nonlinearity depending on a parameter

open access: yesAdvances in Nonlinear Analysis, 2012
The homogeneous Dirichlet problem for an elliptic equation with p-Laplacian and concave-convex reaction term depending on a parameter is investigated.
Marano Salvatore A.   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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