Results 101 to 110 of about 3,662,481 (292)
On some variational algebraic problems
Advances in Nonlinear Analysis, 2013 In this paper by exploiting critical point theory, the existence of two distinct nontrivial solutions for a nonlinear algebraic system with a parameter is established.
Molica Bisci Giovanni, Repovš Dušan
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Multiple solutions for a discrete anisotropic (p_1(k),p_2(k))-Laplacian equations
Electronic Journal of Differential Equations, 2015 This article concerns the existence and multiplicity solutions for a discrete Dirichlet Laplacian problems. Our technical approach is based on variational methods.
El Miloud Hssini
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Evidence for a dual-process account of over-imitation: Children imitate anti- and prosocial models equally, but prefer prosocial models once they become aware of multiple solutions to a task. [PDF]
PLoS One, 2021 Schleihauf H, Hoehl S.
europepmc +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Existence and multiplicity of solutions for nonhomogeneous Klein-Gordon-Maxwell equations
Electronic Journal of Differential Equations, 2015 This article concerns the nonhomogeneous Klein-Gordon-Maxwell equation $$\displaylines{ -\Delta u+u-(2\omega +\phi)\phi u=|u|^{p-1}u +h(x), \quad\text{in }\mathbb{R}^3,\cr \Delta \phi=(\omega +\phi)u^2,\quad\text{in }\mathbb{R}^3, }$$ where ...
Liping Xu, Haibo Chen
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Existence of nontrivial solutions for singular quasilinear equations with sign changing nonlinearity
Electronic Journal of Differential Equations, 2010 By an application of Bonanno's three critical point theorem, we establish the existence of a nontrivial solution to the problem $$displaylines{ -Delta_p u= mu frac{g(x)|u|^{p-2}u}{|x|^p} +lambda a(x)f(u) quad hbox{in }Omega,cr u =0quad hbox{on ...
Jagmohan Tyagi
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source