Results 111 to 120 of about 3,662,481 (292)
Multiple solutions for a class of degenerate nonlocal problems involving sublinear nonlinearities
In this article, we use the three critical points theorem by G. Bonanno [3] in order to investigate the multiplicity of solutions for some nonlocal degenerate problems.
Nguyen Thanh Chung, Hoang Quoc Toan
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Multiplicity of solutions to the sum of polyharmonic equations with critical Sobolev exponents
In this article, we prove multiplicity of solutions for the sum of polyharmonic equation with critical Sobolev exponent. The proof is based upon the methods of weakly lower semi-continuous of the functionals and the Mountain Pass Lemma without (PS ...
Wei Liu, Gao Jia, Lu-Quian Guo
doaj
Multiple Solutions in Euler’s Elastic Problem
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Critical points approaches for multiple solutions of a quasilinear periodic boundary value problem
Optimization problems are omnipresent in the mathematical modeling of real world systems and cover a very extensive range of applications becoming apparent in all branches of Economics, Finance, Materials Science, Astronomy, Physics, Structural and ...
Shapour Heidarkhani +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
We prove a critical-point result which provides conditions for the existence of infinitely many critical points of a strongly indefinite functional with perturbed symmetries.
Monica Clapp +2 more
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source

