Results 91 to 100 of about 73,056 (308)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Low-mass Stellar and Substellar Candidate Companions around Massive Stars in Sco OB1 and M17

open access: yesThe Astronomical Journal
Massive stars are recognized for their high degree of multiplicity, yet the mass ratio regime below 0.1 remains insufficiently explored. It is therefore unknown whether extremely low-mass (possibly substellar) companions can form and survive in the ...
Tinne Pauwels   +3 more
doaj   +1 more source

Multiplicity among Solar-type Stars

open access: yesThe Astrophysical Journal, 2017
Abstract We present a multiplicity census for a volume-complete all-sky survey of 422 stars with distances less than 25 pc and primary main-sequence effective temperatures T eff ≥ 5300 K. Very similar to previous results that have been presented for various subsets of this survey, we confirm the positive correlation of ...
K. Fuhrmann   +3 more
openaire   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Probing the distinct chemical history of the Milky Way halo and old thick disk through HESP-GOMPA survey [PDF]

open access: yesEPJ Web of Conferences
Recent studies of the time-resolved Milky Way formation using asteroseismology have shown that thick disk stars could be very old (0.8 Gyr after the Big Bang, even older than the inner halo).
Saraf Pallavi   +2 more
doaj   +1 more source

Commission 26: Double and Multiple Stars [PDF]

open access: bronze, 2005
William I. Hartkopf   +8 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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