Results 91 to 100 of about 6,328,275 (332)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

V659 Cen: System Members Updated

The Astronomical Journal
V659 Cen is a classical Cepheid which is part of a multiple system. Previous observations have shown that a hot companion dominates an ultraviolet spectrum and a cooler main-sequence star dominates an XMM-Newton spectrum. The Hubble Space Telescope Space
Nancy Remage Evans, Charles Proffitt, Pierre Kervella, Joanna Kuraszkiewicz, H. Moritz Günther, Richard I. Anderson, Alexandre Gallenne, Antoine Mérand, Boris Trahin, Giordano Viviani, Shreeya Shetye   +10 more
doaj   +1 more source

A Swing of the Pendulum: The Chemodynamics of the Local Stellar Halo Indicate Contributions from Several Radial Merger Events

The Astrophysical Journal, 2023
We find that the chemical abundances and dynamics of APOGEE and GALAH stars in the local stellar halo are inconsistent with a scenario in which the inner halo is primarily composed of debris from a single massive, ancient merger event, as has been ...
Thomas Donlon II, Heidi Jo Newberg
doaj   +1 more source

Detection of multiple phase space overdensities of GSE stars by orbit integration [PDF]

, 2023
WenboWu, GangZhao, JiangChang, Xiang-XiangXue, YuqinChen, ChengdongLi, Xianhao Ye, Chengqun Yang   +7 more
openalex   +1 more source

Multiple stellar populations and their influence on blue stragglers

, 2010
It has become clear in recent years that globular clusters are not simple stellar populations, but may host chemically distinct sub-populations, typically with an enhanced helium abundance. These helium-rich populations can make up a substantial fraction
Alexander, Alison Sills, Anders, Angulo, Bedin, Buchler, Böhm-Vitense, Campbell, Cassisi, Chen, Chen, Chen, D'Antona, D'Ercole, De Mink, Dearborn, Decressin, Eggleton, Eggleton, Eldridge, Evert Glebbeek, Ferraro, Ferraro, Ferraro, Formicola, Fujimoto, Fusi Pecci, Glebbeek, Glebbeek, Gratton, Han, Harris, Herwig, Härm, Iben, Iglesias, Kippenhahn, Kippenhahn, Knigge, Kroupa, Leigh, Leigh, Lejeune, Lejeune, Lombardi, Lombardi, Milone, Mocák, Nathan Leigh, Pancino, Piotto, Piotto, Piotto, Pols, Pols, Portegies Zwart, Refsdal, Renzini, Sandage, Saviane, Schlegel, Schröder, Schröder, Sills, Sills, Sills, Sills, Stancliffe, Stancliffe, Ventura, Ventura, Ventura, Ventura, Walker   +73 more
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Multiple star systems observed with CoRoT and Kepler

EPJ Web of Conferences, 2015
The CoRoT and Kepler satellites were the first space platforms designed to perform high-precision photometry for a large number of stars. Multiple systems display a wide variety of photometric variability, making them natural benefactors of these ...
Southworth John
doaj   +1 more source

On the properties of young multiple stars [PDF]

, 2004
We present numerical results on the properties of young binary and multiple stellar systems. Our analysis is based on a series of smoothed particle hydrodynamics (SPH) +N-body simulations of the fragmentation of small molecular clouds, which fully ...
E. Delgado-Donate, C. Clarke, M. Bate, S. Hodgkin   +3 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Bright 22 $\mu$m Excess Candidates from WISE All-Sky Catalog and Hipparcos Main Catalog

, 2013
In this paper we present a catalog which includes 141 bright candidates ($\leq10.27$ mag, V band) showing the infrared (IR) excess at 22 $\mu$m. Of which, 38 stars are known IR excess stars or disk, 23 stars are double or multiple stars and 4 are Be ...
Gao, Liang, Lam, Man-I, Li, Shuo, Wen, Xiao-Qing, Wu, Chao-Jian, Wu, Hong, Yang, Ming, Zhang, Tong-Jie   +7 more
core   +1 more source