Results 101 to 110 of about 77,211 (265)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

SIRIUS: Identifying Metal-poor Stars Enriched by a Single Supernova in a Dwarf Galaxy Cosmological Zoom-in Simulation Resolving Individual Massive Stars

The Astrophysical Journal Letters
Metal-poor stars enriched by a single supernova (mono-enriched stars) are direct proof (and provide valuable probes) of supernova nucleosynthesis. Photometric and spectroscopic observations have shown that metal-poor stars have a wide variety of chemical
Yutaka Hirai, Takayuki R. Saitoh, Michiko S. Fujii, Katsuhiro Kaneko, Timothy C. Beers   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A JWST Project on 47 Tucanae. Overview, Photometry, and Early Spectroscopic Results of M Dwarfs and Observations of Brown Dwarfs

The Astrophysical Journal
James Webb Space Telescope (JWST) observations have been demonstrated to be efficient in detecting multiple stellar populations in globular clusters (GCs) in the low-mass regime of M dwarfs.
A. F. Marino, A. P. Milone, M. V. Legnardi, A. Renzini, E. Dondoglio, Y. Cavecchi, G. Cordoni, A. Dotter, E. P. Lagioia, T. Ziliotto, M. Bernizzoni, E. Bortolan, M. G. Carlos, S. Jang, A. Mohandasan, F. Muratore, M. Tailo   +16 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Least Common Multiple of a Cycle and a Star

Electronic Notes in Discrete Mathematics, 2003
Abstract A graph G is decomposable into the subgraphs G1, G2,…, Gn of G if no Gi, (i = 1, 2,…, n) has isolated vertices and the edge set E(G) can be partitioned into the subsets E(G1),E(G2),…, E(Gn). If Gi ≈ H for every i, we say that G is H-decomposable and we write H∣G. A graph F without isolated vertices is a least common multiple of the graphs G1
openaire   +1 more source

Photometric Identification of Unresolved Binary Stars in Nearby Open Star Clusters

The Astrophysical Journal
This paper introduces a new method to search for unresolved binary stars in open star clusters. The work aims at improving the approach introduced previously, which employs the (H − W2) − W1 versus W2 − (BP − K) photometric diagram.
Varvara O. Mikhnevich, Anastasiia Plotnikova, Giovanni Carraro, Anton F. Seleznev   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source