Results 141 to 150 of about 5,074,994 (301)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Shortest Period for Outer Orbit in Compact Hierarchical Triple? Discovery of SB1 Around V 885 Per

open access: yesThe Astronomical Journal
I present a discovery of SB1 in the LAMOST-MRS spectra of eclipsing contact binary V 885 Per. Spectroscopic orbit has period only P = 21.8 days, which will make it shortest known outer period in compact hierarchical triple system, if this SB1 is indeed ...
Mikhail Yu. Kovalev
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Multiple stars: Physics vs. dynamics

open access: yes, 2020
We review physical and dynamical parameters of multiple stars. Possible scenaria of multiple star formation are discussed: their birth in dense cloud cores and the decay of small stellar groups and clusters.
Rubinov A., Orlov V., Zhuchkov R.
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Presupernova Multiple Giant Eruptions in Massive Stars

open access: yesThe Astrophysical Journal
Massive stars can exhibit giant eruptions with high mass loss shortly before their explosion as a core-collapse supernova. These multiple giant eruptions (MGEs) may have a commutative effect that brings the star to a different state, possibly one that ...
Bhawna Mukhija, Amit Kashi
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Physical parameters of three field RR Lyrae stars [PDF]

open access: yes, 2013
This work was partially supported by DGAPA–Universidad Nacional Autonoma de Mexico through project IN104612.Stromgren uvby - beta photometry of the stars classified as RR Lyrae stars RU Piscium, SS Piscium and TU Ursae Majoris has been used to estimate ...
Jaimes, R. Figuera   +2 more
core  

Southern Binaries with the Zorro Speckle Camera @ Gemini South

open access: yesThe Astronomical Journal
We present measurements in the context of a survey of southern hemisphere binary and multiple stellar systems observed with the Zorro Speckle dual diffraction-limited optical imaging camera on the 8.1 m Gemini South telescope carried out between 2019 and
Rene A. Mendez   +3 more
doaj   +1 more source

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