Results 151 to 160 of about 6,328,275 (332)

Reading the book: from "chemical anomalies" to "standard composition" of globular clusters

open access: yes, 2013
It is now commonly accepted that globular clusters (GCs) have undergone a complex formation and that they host at least two stellar generations. This is a recent paradigm and is founded on both photometric and spectroscopic evidence.
Bragaglia, Angela   +5 more
core  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Identifying Hierarchically Triple Star Systems with Gaia DR3 and LAMOST

open access: yesThe Astronomical Journal
Triple star systems are critical for understanding stellar dynamics and compact objects in astrophysics, yet confirmed hierarchical triples identified via spectroscopy remain limited.
Tongyu He   +10 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Evolutionary States and Triplicity of Four Massive Semidetached Binaries with Long-term Decreasing Orbital Periods in the LMC

open access: yesThe Astrophysical Journal
The massive semidetached binary with a long-term decreasing orbital period may involve a rapid mass-transfer phase in Case A, and thus, they are good astrophysical laboratories for investigating the evolution of massive binary stars.
Fu-Xing Li   +8 more
doaj   +1 more source

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