Haro 5-2: A New Pre-main-sequence Quadruple Stellar System
The Astronomical JournalWe have discovered that the H α emission-line star Haro 5-2, located in the 3–6 Myr old Ori OB1b association, is a young quadruple system. The system has a 2+2 configuration, with an outer separation of 2.″6 and with resolved subarcsecond inner binary ...
Bo Reipurth +11 more
doaj +1 more source
Fourier Analysis ofHubble Space TelescopeFine Guidance Sensor Data of Binary Stars and Application to the Multiple System HD 157948 [PDF]
, 2006 Elliott P. Horch +3 more
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Molecular Oncology, EarlyView.Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
Southern Very Low Mass Stars and Brown Dwarfs in Wide Binary and Multiple Systems [PDF]
, 2007 J. A. Caballero
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Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Speckle interferometry of nearby multiple stars. IV. Measurements in 2004 and new orbits [PDF]
, 2007 И. И. Балега +6 more
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Multiple Stellar Populations in Asymptotic Giant Branch Stars of Galactic Globular Clusters [PDF]
, 2021 E. P. Lagioia +10 more
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Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source