Results 161 to 170 of about 6,328,275 (332)

THE INFRARED EYE OF THE WIDE-FIELD CAMERA 3 ON THE HUBBLE SPACE TELESCOPE REVEALS MULTIPLE MAIN SEQUENCES OF VERY LOW MASS STARS IN NGC 2808 [PDF]

, 2012
A. P. Milone, A F Marino, S. Cassisi, G. Piotto, L. R. Bedin, J. Anderson, F. Allard, A. Aparicio, A Bellini, R. Buonanno, M. Monelli, A. Pietrinferni, A. P. Milone, A F Marino, S. Cassisi, G. Piotto, L. R. Bedin, J. Anderson, F. Allard, A. Aparicio, A Bellini, R. Buonanno, M. Monelli, A. Pietrinferni   +23 more
openalex   +1 more source

Hidden Companions to Intermediate-mass Stars. IX. Discovery of a 1.5 M _⊙, 1 au Companion to the Primary within the Multiple HIP 57606*

, 2023
Idel Waisberg, Ygal Klein, Boaz Katz
openalex   +1 more source

The GALAH survey: Multiple stars and our Galaxy. I. A comprehensive method for deriving properties of FGK binary stars [PDF]

, 2020
G. Traven, S. Feltzing, T. Merle, M. Van der Swaelmen, Klemen Čotar, Ross P. Church, T. Zwitter, Yuan-Sen Ting, C. Sahlholdt, M. Asplund, Joss Bland‐Hawthorn, G. De Silva, K. C. Freeman, Sarah L. Martell, Sanjib Sharma, D. B. Zucker, Sven Buder, Andrew R. Casey, V. D’Orazi, Janez Kos, Geraint F. Lewis, J. Lin, K. Lind, Jeffrey D. Simpson, Dennis Stello, U. Munari, Robert A. Wittenmyer   +26 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Search and identification of high-velocity stars by dynamical ejection and supernovae from multiple stars

, 2023
V. Hambaryan, R. Neuhäeuser
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Detection of Two Totally Eclipsing B-type Binaries with Extremely Low Mass Ratios

The Astrophysical Journal
The detection of O- and B-type stars with extremely low-mass companions is very important for understanding the formation and evolution of binary stars. However, finding them remains a challenge because the low-mass components in such systems contribute ...
Linfeng Chang, Shengbang Qian, Lei Zang, Fuxing Li   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

CSI 2264: SIMULTANEOUS OPTICAL AND INFRARED LIGHT CURVES OF YOUNG DISK-BEARING STARS IN NGC 2264 WITHCoRoTandSPITZER—EVIDENCE FOR MULTIPLE ORIGINS OF VARIABILITY [PDF]

, 2014
Ann Marie Cody, J. R. Stauffer, A. Baglin, G. Micela, L. M. Rebull, E. Flaccomio, M. Morales‐Calderón, S. Aigrain, J. Bouvier, Lynne A. Hillenbrand, Robert Gutermuth, Inseok Song, N. Turner, S. H. P. Alencar, K. Zwintz, Peter Plavchan, John M. Carpenter, K. Findeisen, S. Carey, S. Terebey, Lee Hartmann, Nuria Calvet, P. S. Teixeira, F. J. Vrba, S. J. Wolk, Kevin R. Covey, Katja Poppenhaeger, Hans Moritz Günther, Jan Forbrich, B. A. Whitney, L. Affer, W. Herbst, Joseph L. Hora, D. Barrado, Jon A. Holtzman, Franck Marchis, Kenneth Wood, M. M. Guimarães, J. Lillo-Box, Edward Gillen, A. McQuillan, Catherine Espaillat, Lori Allen, Paola D’Alessio, F. Favata   +44 more
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source