Results 221 to 230 of about 5,074,994 (301)

Domain-specific physical activity levels and risk of dementia: a systematic review and meta-analysis. [PDF]

Lancet Public Health
Feter N, Iso-Markku P, Markarian T, Luong DM, Gunnink J, Schröder N, Caputo EL, Feter J, Nanda A, Hourihan S, da Silva GS, Ventura A, Bumaguin DB, Klimentidis YC, Alexander GE, Umpierre D, Hallal PC, Rombaldi AJ, Raichlen DA.   +18 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Squamous dedifferentiation and differentiated high-grade transformation of papillary thyroid carcinoma in metastatic lymph nodes: Two cases and literature review. [PDF]

Radiol Case Rep
Salih AM, Ali RM, Abdullah AM, Habibullah IJ, Hammood ZD, Abdulkarim MM, Qadir AA, Ahmed HA, Hassan SH, Kakamad FH.   +9 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Systemic immunosuppression limits NK cell therapy efficacy in pancreatic cancer. [PDF]

Mol Cancer
He C, Wang D, Hu T, Gonzalez D, Thakur R, Matysniak DP, King RJ, Kollala SS, Markov SD, Fujii Y, Tej GNVC, Zhao J, Jin L, Oberley-Deegan R, Shukla SK, Zhang XA, Friedman JE, Singh PK, Hollingsworth MA, di Magliano MP, Crawford HC, Mehla K.   +21 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

When dermoscopy of a nodule on the hysterectomy scar reveals peritoneal carcinomatosis from high-grade serous tubal carcinoma. [PDF]

Oxf Med Case Reports
Benchekroun K, Ghaleb M, Gallouj S, Eljouari O.   +3 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Identifying Prognostic Factors Implicated in Chronic Functional Abdominal Pain in Children: A Systematic Review. [PDF]

Gastroenterology Res
Richardson H, Bland R, Gray K.
europepmc   +1 more source