Results 81 to 90 of about 73,056 (308)

TIC 290061484: A Triply Eclipsing Triple System with the Shortest Known Outer Period of 24.5 Days

open access: yesThe Astrophysical Journal
We have discovered a triply eclipsing triple-star system, TIC 290061484, with the shortest known outer period, P _out , of only 24.5 days. This “eclipses” the previous record set by λ Tauri at 33.02 days, which held for 68 yr.
V. B. Kostov   +15 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Symmetrization of the Berezin star product and multiple star product method [PDF]

open access: yesJournal of Physics A: Mathematical and General, 2001
We construct a multiple star product method and by using this method, show that integral forms of some star products can be written in terms of the path-integral. This method can be applied to some examples. Especially, the associativity of the skew-symmetrized Berezin star product proposed in \cite{SW}, is recovered in large $N$ limit of the multiple ...
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Multiplicity of Massive Stars [PDF]

open access: yes, 2007
We review the multiplicity of massive stars by compiling the abstracts of the most relevant papers in the field. We start by discussing the massive stars in the Orion Trapezium Cluster and in other Galactic young clusters and OB associations, and end with the R136 cluster in the LMC.
openaire   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

CHARACTERIZATIONS OF GRADED PRÜFER ⋆-MULTIPLICATION DOMAINS [PDF]

open access: yesKorean Journal of Mathematics, 2014
Let $R=\bigoplus_{ \in }R_ $ be a graded integral domain graded by an arbitrary grading torsionless monoid $ $, and $\star$ be a semistar operation on $R$. In this paper we define and study the graded integral domain analogue of $\star$-Nagata and Kronecker function rings of $R$ with respect to $\star$.
openaire   +6 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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