Results 231 to 240 of about 238,223 (293)

Robust spectral averaging and chemical shift calculation for hyperpolarized ¹²⁹Xe MR spectroscopy. [PDF]

Magn Reson Imaging
Lee SN, Leewiwatwong S, Costelle A, Mummy D, Driehuys B.   +4 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Retraction: Establishment of a non-small-cell lung cancer-liver metastasis patient-derived tumor xenograft model for the evaluation of patient-tailored chemotherapy. [PDF]

Biosci Rep
Yang X, Meng G.
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Toward model-guided electrophysiology-Encoding of chirps in the electrosensory periphery of <i>Apteronotus leptorhynchus</i>. [PDF]

Front Comput Neurosci
Barayeu A, Benda J, Grewe J.
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Utility of First-Trimester Combined Screening Markers for Identifying Pregnancy at Increased Risk of Fetal Chromosomal Abnormalities. [PDF]

Cureus
Kumawat R, Sharma H, Nimesh A, Sinha S, Kaur H, Kumar P, Priya I, Goyal G.   +7 more
europepmc   +1 more source

[Tuberculosis screening in young migrants from Mali: concordance between Mantoux and QuantiFERON® in Primary Care]. [PDF]

Aten Primaria
Hidalgo Rípodas Í, Elizalde Sanabria A.   +1 more
europepmc   +1 more source

Adults With Acid Sphingomyelinase Deficiency Have Sustained Improvements in Clinical Outcomes With up to 5 Years of Olipudase Alfa Enzyme Replacement Therapy: ASCEND Trial Final Results. [PDF]

J Inherit Metab Dis
Wasserstein MP, Hollak CE, Barbato A, Gallagher RC, Giugliani R, Guelbert NB, Hennermann JB, Ikezoe T, Lachmann R, Lidove O, Mabe P, Mengel E, Scarpa M, Senates E, Tchan M, Thurberg BL, Villarrubia J, Armstrong NM, Bhushan S, Kim Y, Kumar M.   +20 more
europepmc   +1 more source

Timed and targeted transfusion in Rh isoimmunization: A case report on early detection and neonatal outcomes. [PDF]

Qatar Med J
Haroon S, Aggarwal M, Hussain H, Sugathan A, Rao S, Kumar NA.   +5 more
europepmc   +1 more source