Results 1 to 10 of about 221,833 (246)

THE EDUCATION SYSTEM AND LEGAL VALUES [PDF]

open access: yesSupremația Dreptului, 2021
The systemic perspective on the educational phenomenon reveals, among others, its complexity and interactions as a social process of formation, development and social integration of the human personality, of transmitting the social experience and of the ...
Ion CRAIOVAN, Bogdan CUZA
doaj   +1 more source

Viroscope: Plant viral diagnosis from high-throughput sequencing data using biologically-informed genome assembly coverage

open access: yesFrontiers in Microbiology, 2022
High-throughput sequencing (HTS) methods are transforming our capacity to detect pathogens and perform disease diagnosis. Although sequencing advances have enabled accessible and point-of-care HTS, data analysis pipelines have yet to provide robust tools
Sandro L. Valenzuela   +8 more
doaj   +1 more source

Cyclic microchip assay for measurement of hundreds of functional proteins in single neurons

open access: yesNature Communications, 2022
Current single-cell tools are limited by the number of proteins they can analyse. Here the authors report a single-cell cyclic multiplex in situ tagging (CycMIST) method for functional proteome profiling of single cells, allowing multiple rounds of ...
Liwei Yang   +7 more
doaj   +1 more source

Single-Cell Spatial MIST for Versatile, Scalable Detection of Protein Markers

open access: yesBiosensors, 2023
High-multiplex detection of protein biomarkers across tissue regions has been an attractive spatial biology approach due to significant advantages over traditional immunohistochemistry (IHC) methods. Different from most methods, spatial multiplex in situ
Arafat Meah   +7 more
doaj   +1 more source

Humoral immune response to SARS-CoV-2 and endemic coronaviruses in urban and indigenous children in Colombia

open access: yesCommunications Medicine, 2023
Background Although anti-SARS-CoV-2 humoral immune responses and epidemiology have been extensively studied, data gaps remain for certain populations such as indigenous people or children especially in low- and middle-income countries.
Nathalie Verónica Fernández Villalobos   +14 more
doaj   +1 more source

Increasing the Efficiency of Canola and Soybean GMO Detection and Quantification Using Multiplex Droplet Digital PCR

open access: yesBiology, 2022
The number of genetically modified (GM) events for canola, maize, and soybean has been steadily increasing. Real-time PCR is widely used for the detection and quantification of individual GM events.
Tigst Demeke, Sung-Jong Lee, Monika Eng
doaj   +1 more source

A Variable Height Microfluidic Device for Multiplexed Immunoassay Analysis of Traumatic Brain Injury Biomarkers

open access: yesBiosensors, 2021
Traumatic brain injury (TBI) is a leading cause of global morbidity and mortality, partially due to the lack of sensitive diagnostic methods and efficacious therapies.
Alyse D. Krausz   +2 more
doaj   +1 more source

A Robust and Fast/Multiplex Pharmacogenetics Assay to Simultaneously Analyze 17 Clinically Relevant Genetic Polymorphisms in CYP3A4, CYP3A5, CYP1A2, CYP2C9, CYP2C19, CYP2D6, ABCB1, and VKORC1 Genes

open access: yesPharmaceuticals, 2022
In the field of pharmacogenetics, the trend is to analyze a panel of several actionable genetic polymorphisms. It may require the use of high-throughput sequencing which demands expensive reagents/instruments and specific skills to interpret results.
Camille Tron   +7 more
doaj   +1 more source

A Diagnostic Gene Expression Signature for Bladder Cancer Can Stratify Cases into Prescribed Molecular Subtypes and Predict Outcome

open access: yesDiagnostics, 2022
Bladder cancer is a biologically heterogeneous disease with variable clinical presentations, outcomes and responses to therapy. Thus, the clinical utility of single biomarkers for the detection and prediction of biological behavior of bladder cancer is ...
Runpu Chen   +9 more
doaj   +1 more source

New Flowering and Architecture Traits Mediated by Multiplex CRISPR-Cas9 Gene Editing in Hexaploid Camelina sativa

open access: yesAgronomy, 2022
Adapting plants to sustainable cropping systems is a major challenge for facing climate change and promoting agroecological transition. Camelina sativa is an emerging oilseed crop species with climate-resilient properties that could be used in double ...
Yannick Bellec   +7 more
doaj   +1 more source

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