Results 71 to 80 of about 31,893 (252)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Quantifying layer similarity in multiplex networks: a systematic study [PDF]

Royal Society Open Science, 2018
Computing layer similarities is an important way of characterizing multiplex networks because various static properties and dynamic processes depend on the relationships between layers.
Piotr Bródka, Anna Chmiel, Matteo Magnani, Giancarlo Ragozini   +3 more
doaj   +1 more source

Weak percolation on multiplex networks [PDF]

Physical Review E, 2014
14 pages, 12 ...
Baxter, Gareth J., Dorogovtsev, Sergey N., Mendes, José F.F., Cellai, Davide   +3 more
openaire   +5 more sources

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

The multiplex network of human diseases [PDF]

npj Systems Biology and Applications, 2017
Untangling the complex interplay between phenotype and genotype is crucial to the effective characterization and subtyping of diseases. Here we build and analyze the multiplex network of 779 human diseases, which consists of a genotype-based layer and a phenotype-based layer. We show that diseases with common genetic constituents tend to share symptoms,
Arda Halu, Manlio De Domenico, Alex Arenas, Amitabh Sharma   +3 more
openaire   +4 more sources

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

Information Spreading on Weighted Multiplex Social Network

Complexity, 2019
Information spreading on multiplex networks has been investigated widely. For multiplex networks, the relations of each layer possess different extents of intimacy, which can be described as weighted multiplex networks.
Xuzhen Zhu, Jinming Ma, Xin Su, Hui Tian, Wei Wang, Shimin Cai   +5 more
doaj   +1 more source

Relay synchronization in multiplex networks [PDF]

Scientific Reports, 2018
AbstractRelay (or remote) synchronization between two not directly connected oscillators in a network is an important feature allowing distant coordination. In this work, we report a systematic study of this phenomenon in multiplex networks, where inter-layer synchronization occurs between distant layers mediated by a relay layer that acts as a ...
I. Leyva, I. Sendiña-Nadal, R. Sevilla-Escoboza, V. P. Vera-Avila, P. Chholak, S. Boccaletti   +5 more
openaire   +4 more sources