Results 141 to 150 of about 877,269 (241)
Qrt-PCR validation of 12randomly selected differentially expressed genes (DEGs) detected by RNA-seq.
, 2018 Qrt-PCR validation of 12randomly selected differentially expressed genes (DEGs) detected by RNA-seq.
ShengChao Zhao (5513588) +3 more
core +1 more source
HOX gene analysis in the osteogenic differentiation of human mesenchymal stem cells
Genetics and Molecular Biology, 2008 Human bone marrow-derived mesenchymal stem cells (hMSCs) have the capacity to differentiate into osteoblasts during osteogenesis. Several studies attempted to identify osteogenesis-related genes in hMSCs.
Song Wha Chae +8 more
doaj
Multiplex electrochemical sensing platforms for the detection of breast cancer biomarkers
Frontiers in Medical TechnologyHerein, advancements in electroanalytical devices for the simultaneous detection of diverse breast cancer (BC) markers are demonstrated. This article identifies several important areas of exploration for electrochemical diagnostics and highlights ...
Connor O’Brien +3 more
doaj +1 more source
Single‐Nucleus RNA Sequencing Identifies CREM as a Brake on Myofiber Hypertrophy in Chickens
Advanced Science, EarlyView.Single‐nucleus RNA sequencing on 91 144 nuclei from postnatal chicken pectoralis major between fast‐growing broilers (FG) and slow‐growing layers (SG) identifies the transcriptional factor CREM as a novel brake of myofiber hypertrophy. Mechanistically, functional validation experiments confirm that CREM activates the promoter of JUN and CREM deletion ...
Shuang Gu +12 more
wiley +1 more source
QRT-PCR validation of 7 miRNAs.
, 2018 (A) The small RNA-Seq log2 value (expression ratios of S03-RPKM/S04-RPKM) and the qRT-PCR log2 value (expression ratios of S03/S04) of three important miRNAs (bna-miR156e, conservative-chrA05-439469 and unconservative-chrCnn-random-3253054) which the ...
Zhipeng Niu (3519488) +7 more
core +1 more source
Advanced Science, EarlyView.Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng +7 more
wiley +1 more source
qRT-PCR analysis of MALAT-1 expression in transfected ovarian cells.
, 2016 (A) qRT-PCR analysis of MALAT-1 expression following shRNA knockdown. OVCAR3 cells were grown and transfected with four different MALAT-1 shRNA vectors (shM1 to shM4) and then subjected to qRT-PCR analysis.
Xiaying Xu (3166854) +7 more
core +1 more source
Loss of Lepr in Fibroblasts Drives Tumor Development by Promoting Macrophage Infiltration
Advanced Science, EarlyView.TNFα and TGFβ signaling reprograms Lepr+ fibroblasts toward a LeprnegMmphigh inflammatory CAF (iCAF) state, with downregulation of the Tcf21‐Lepr axis contributing to this transition. Lepr loss induces Csf3, which contributes to the enhanced macrophage‐recruiting capacity of these iCAFs, thereby promoting tumor development. Thus, inflammatory signaling
Manyu Song +13 more
wiley +1 more source
Advanced Science, EarlyView.ANGPTL4 exhibits distinct promoter methylation patterns and expression profiles in EBV‐positive versus EBV‐negative gastric cancer. Secreted C‐terminal ANGPTL4 (cANGPTL4) acts as the dominant functional isoform driving GC proliferation, EMT, and neutrophil infiltration. cANGPTL4 promotes neutrophil recruitment via NF‐κB/CXCL8 axis.
Dandan Li +10 more
wiley +1 more source
qRT-PCR primers sequence used in Fig 3A and S3E Fig.
, 2018 qRT-PCR primers sequence used in Fig 3A and S3E Fig.
Supriyo De (242463) +7 more
core +1 more source