Background and Purpose Neuronal plasticity enables the brain to adapt to internal and external demands by dynamically regulating synaptic connectivity and emotional circuitry. Impaired neuroplasticity represents a core pathophysiological framework of major depressive disorder, one of the leading causes of disability worldwide. Chronic stress is a major
Paola Brivio +11 more
wiley +1 more source
A heterozygous deletion and inversion at the NHEJ1‑IHH locus associated with shank length in Yunlong short-leg chicken. [PDF]
Xu K +8 more
europepmc +1 more source
HuR Confers Resistance of Hepatocellular Carcinoma to Lenvatinib by Inhibiting Ferroptosis
ABSTRACT This study aim to explore whether human antigen R (HuR) inhibits ferroptosis confers resistance to lenvatinib in hepatocellular carcinoma (HCC). Bioinformatics analysis and immunofluorescence detection of 30 HCC tissue samples were used to verify the clinical correlation between HuR and glutathione peroxidase 4 (GPX4), establish a lenvatinib ...
Siren Feng +9 more
wiley +1 more source
Multimodal genomic surveillance for respiratory pathogens at four U.S. international airports: A comparison of air, wastewater, clinical, and national surveillance data. [PDF]
Gratalo D +13 more
europepmc +1 more source
Characterisation of human hair follicle development
Schematic of hair follicle development in human skin. Hair follicle primordia of similar sizes, but different densities, are laid out across the skin. The distinction between terminal and vellus hair sites is not obvious at early stages of hair follicle development.
Zoe R. Sudderick +4 more
wiley +1 more source
Development of a multiplex fluorescent qPCR assay for the simultaneous detection of bovine viral diarrhea virus and pathogenic Escherichia coli. [PDF]
Zhu W, Zhu H.
europepmc +1 more source
Osmotic stressors induce developmental and physiological changes in rice (Oryza sativa) seedlings, which are modulated by cell‐type‐specific gene expression and regulatory networks. We exposed plants to two levels of drought and salinity stress and measured the effects of these stressors on developing leaves by measuring physiological traits, ion ...
Sean M. Robertson +6 more
wiley +1 more source
SUMMARY Plants employ cell‐type‐specific transcriptional programs to defend against pathogens, yet the cellular heterogeneity of immune responses in the medicinal orchid Dendrobium officinale Kimura et Migo remains largely unexplored. A single‐cell transcriptomic atlas of the D.
Lingli Li +5 more
wiley +1 more source
A novel tRNA-derived fragment, tRF-19-79MP9PJZ, promotes uterine corpus endometrial carcinoma progression by targeting DSC3. [PDF]
Jiang H +4 more
europepmc +1 more source
GHSR and TLR4 collectively promote hepatic inflammation and aberrant repair in alveolar echinococcosis. [PDF]
Chen G +7 more
europepmc +1 more source

