Results 101 to 110 of about 1,907,812 (295)

DataSheet_1_Strategies for Accurate Cell Type Identification in CODEX Multiplexed Imaging Data.pdf

, 2021
Multiplexed imaging is a recently developed and powerful single-cell biology research tool. However, it presents new sources of technical noise that are distinct from other types of single-cell data, necessitating new practices for single-cell ...
Yury Goltsev (356992), Yuqi Tan (1409995), Garry P. Nolan (201798), John W. Hickey (4497922)   +3 more
core   +1 more source

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Advanced Healthcare Materials, EarlyView.
Systematic investigation of antibody orientation strategies in lateral flow immunoassays reveals that a para‐substituted (aminomethyl)phenylboronic acid mediated probe (P‐6) combined with a biotin‐streptavidin test‐line modification achieves a synergistic 14‐ to 19‐fold sensitivity gain over conventional conjugation. Furthermore, multiplexed detection,
Pin‐Hao Wang, Shunmuga Nathan Shunmuga Nainar, Bing‐Han Zhuang, Shun‐Mao Yang, Hong‐Cheu Lin, Yang‐Hsiang Chan   +5 more
wiley   +1 more source

Table_1_Strategies for Accurate Cell Type Identification in CODEX Multiplexed Imaging Data.xlsx

, 2021
Multiplexed imaging is a recently developed and powerful single-cell biology research tool. However, it presents new sources of technical noise that are distinct from other types of single-cell data, necessitating new practices for single-cell ...
Yury Goltsev (356992), Yuqi Tan (1409995), Garry P. Nolan (201798), John W. Hickey (4497922)   +3 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

POSA for fast, amplified and multiplexed protein imaging

Nature Communications
Fluorescent π-conjugated polymers (FCPs) are known for their superior brightness but are still unavailable for highly multiplexed molecular imaging in single cells as they are hydrophobic and lack targeting capability toward biomolecules.
Wenkang Zhang, Hengfeng Jiang, Liang Han, Jie Liu, Jie Wang, Feng He, Leilei Tian   +6 more
doaj   +1 more source

Seamless Mechanical Programming Through Hybrid Epoxy–Acrylate Printing for Soft–Rigid Robots

Advanced Materials, EarlyView.
Hybrid epoxy‐acrylate printing enables seamless fabrication of soft–rigid robotic systems with covalently integrated interfaces and functionally graded mechanics. Grayscale exposure expands the accessible material space, enabling spatially programmed actuation through patterned stiffness while revealing the mechanics and durability of continuously ...
David C. Bershadsky, Franz A. Stolpen, Zachariah A. Page, Lillian Chin   +3 more
wiley   +1 more source

From density to spatial function: spatial multi-omics, composite biomarker design, and therapeutic engineering of tertiary lymphoid structures in solid tumors

Frontiers in Immunology
BackgroundTertiary lymphoid structures (TLSs) have emerged as clinically relevant immune niches associated with improved survival and enhanced response to immune checkpoint inhibitors across multiple solid tumors.
Xuchen Wang, Lin Lin
doaj   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Monolithically 3D‐Printed Spectral‐Spatial Meta‐Authenticators

Advanced Materials, EarlyView.
A single height map printed in a low‐index resin by two‐photon lithography encodes multiple visible wavelengths in one metasurface without any polarization optics. A fabrication‐aware optimization folds the printable height levels into the design, so the device is printed as optimized.
Cherry Park, Shiqi Hu, Youngsun Jeon, Junsuk Rho   +3 more
wiley   +1 more source

Culinary Chemistry as a Platform for Interfacial Materials Design

Advanced Materials Interfaces, EarlyView.
Culinary processes control interfaces through heating, shear, gelation, and molecular transport. This Review connects selected gastronomic examples with food‐derived nanomaterials, plasmonic sensing, anthocyanin photovoltaics, and intelligent packaging. Original agar‐based plasmonic films illustrate the proposed translation.
Josep Moreno, I. Brian Becerril‐Castro, Irene Calderon‐Gonzalez, Jaslyn Ru Ting Chen, Zhiming Wang, Alexander O. Govorov, José Manuel Romo‐Herrera, Neus Feliu, Wolfgang J. Parak, Miguel A. Correa‐Duarte, In Yee Phang, Xing Yi Ling, Ramón A. Alvarez‐Puebla   +12 more
wiley   +1 more source