Results 121 to 130 of about 3,600,628 (280)

DNA-barcoded signal amplification for imaging mass cytometry enables sensitive and highly multiplexed tissue imaging. [PDF]

Nat Methods, 2023
Hosogane T, Casanova R, Bodenmiller B.
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

UniFORM: Towards Universal ImmunoFluorescence Normalization for Multiplex Tissue Imaging

Abstract Multiplexed tissue imaging (MTI) technologies enable high-dimensional spatial analysis of tumor microenvironments but face challenges with technical variability in staining intensities. Existing normalization methods, including Z-score, ComBat, and MxNorm, often fail to account for the heterogeneous, right-skewed expression ...
Kunlun Wang, Kaoutar Ait-Ahmad, Sam Kupp, Zachary Sims, Eric Cramer, Zeynep Sayar, Jessica Yu, Melissa H. Wong, Gordon B. Mills, S. Ece Eksi, Young Hwan Chang   +10 more
openaire   +2 more sources

Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data. [PDF]

IEEE Trans Vis Comput Graph, 2023
Warchol S, Krueger R, Nirmal AJ, Gaglia G, Jessup J, Ritch CC, Hoffer J, Muhlich J, Burger ML, Jacks T, Santagata S, Sorger PK, Pfister H.   +12 more
europepmc   +1 more source

Integrated system for ultrasonic, elasticity and photoacoustic imaging [PDF]

, 2008
textBy integrating three complementary imaging techniques - ultrasound, elasticity and photoacoustic imaging, a hybrid imaging system utilizing an array transducer is proposed for various biomedical imaging applications including cancer detection ...
Park, Suhyun, 1977-
core  

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

3D multiplexed tissue imaging reconstruction and optimized region of interest (ROI) selection through deep learning model of channels embedding. [PDF]

Front Bioinform, 2023
Burlingame E, Ternes L, Lin JR, Chen YA, Kim EN, Gray JW, Chang YH.   +6 more
europepmc   +1 more source

Statistical methods and computational tools for normalization and spatial analysis of multiplexed imaging data

, 2022
Multiplexed imaging is a nascent single-cell assay that can be used to understand and analyze complex processes in tissue-based cancers, autoimmune disorders, and more.
Harris, Coleman Reed
core  

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source