Results 51 to 60 of about 373,830 (305)
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
IET Microwaves, Antennas & Propagation, 2021 A novel approach to de‐embed the frequency response of filters connected to a 2‐channel multiplexer without the need for unplugging is proposed. The technique to manifold coupled multiplexers with arbitrary number of filters is also theoretically ...
Sayyed Reza Mirnaziry +3 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Design of Bandpass Multiplexer-Integrated Power Dividers
IEEE Access, 2022 This study proposed a novel methodology for designing bandpass multiplexer-integrated power dividers (PDs) that provide frequency division, frequency selection, and power division. New coupling schemes for the multiplexer-integrated PDs were presented to
Chi-Feng Chen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Dual-Band Waveform Generator With Ultra-Wide Low-Frequency Tuning-Range
IEEE Access, 2016 This paper presents a novel mixed-signal low-power dual-band square/triangular waveform generator (WFG) chip with a wide low-frequency tuning range for medical bio-electric stimulation therapy.
Ibtisam A. Abbas Al-DARKAZLY +1 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Analysis and Synthesis of Single-Bit Adders for Multi-Bit Adders with Sequential Transfers
Engineering ProceedingsThis paper provides an analysis of existing single-digit binary adders from the point of view of their implementation on fans built based on metal-oxide-semiconductor field-effect transistor—MOSFETs.
Sakhybay Tynymbayev +5 more
doaj +1 more source
Exposure Synchronization in Optical Camera Communications for Time Division Multiplexing [PDF]
, 2023 Hiroaki Matsunaga +3 more
openalex +1 more source