Results 51 to 60 of about 88,556 (313)

Weighted Multiplex Networks

PLoS ONE, 2014
One of the most important challenges in network science is to quantify the information encoded in complex network structures. Disentangling randomness from organizational principles is even more demanding when networks have a multiplex nature. Multiplex networks are multilayer systems of $N$ nodes that can be linked in multiple interacting and co ...
MENICHETTI, GIULIA, REMONDINI, DANIEL, Panzarasa P, Mondragón RJ, Bianconi G.   +4 more
openaire   +6 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

An Ultra-Energy-Efficient Reversible Quantum-Dot Cellular Automata 8:1 Multiplexer Circuit

Quantum Reports
Energy efficiency considerations in terms of reduced power dissipation are a significant issue in the design of digital circuits for very large-scale integration (VLSI) systems.
Mohammed Alharbi, Gerard Edwards, Richard Stocker   +2 more
doaj   +1 more source

Wavelength-division-multiplexing (WDM)-based integrated electronic–photonic switching network (EPSN) for high-speed data processing and transportation

Nanophotonics, 2020
Integrated photonics offers attractive solutions for realizing combinational logic for high-performance computing. The integrated photonic chips can be further optimized using multiplexing techniques such as wavelength-division multiplexing (WDM).
Feng Chenghao, Ying Zhoufeng, Zhao Zheng, Gu Jiaqi, Pan David Z., Chen Ray T.   +5 more
doaj   +1 more source

Design of Ternary Logic and Arithmetic Circuits Using GNRFET

IEEE Open Journal of Nanotechnology, 2020
Multiple valued logic (MVL) can represent an exponentially higher number of data/information compared to the binary logic for the same number of logic bits.
Zarin Tasnim Sandhie, Farid Uddin Ahmed, Masud H. Chowdhury   +2 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A practical de‐embedding technique based on the network theory for the filters in a 2‐channel multiplexer

IET Microwaves, Antennas & Propagation, 2021
A novel approach to de‐embed the frequency response of filters connected to a 2‐channel multiplexer without the need for unplugging is proposed. The technique to manifold coupled multiplexers with arbitrary number of filters is also theoretically ...
Sayyed Reza Mirnaziry, Ali Kheirdoost, Maysam Haghparast, Ali Akbar Ahmadi   +3 more
doaj   +1 more source

Design of Bandpass Multiplexer-Integrated Power Dividers

IEEE Access, 2022
This study proposed a novel methodology for designing bandpass multiplexer-integrated power dividers (PDs) that provide frequency division, frequency selection, and power division. New coupling schemes for the multiplexer-integrated PDs were presented to
Chi-Feng Chen, Hsin-Ya Tseng, Yi-Hua He, Wen-Jie Le   +3 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source