Results 41 to 50 of about 290,770 (278)

Ultrabright Fluorescent Silica Nanoparticles for Multiplexed Detection

Nanomaterials, 2020
Fluorescent tagging is a popular method in biomedical research. Using multiple taggants of different but resolvable fluorescent spectra simultaneously (multiplexing), it is possible to obtain more comprehensive and faster information about various ...
Saquib Ahmed M. A. Peerzade, Nadezda Makarova, Igor Sokolov   +2 more
doaj   +1 more source

Multiplexing Free-Space Channels using Twisted Light [PDF]

, 2015
We experimentally demonstrate an interferometric protocol for multiplexing optical states of light, with potential to become a standard element in free-space communication schemes that utilize light endowed with orbital angular momentum (OAM).
Boyd, Robert W., Chen, Changchen, Magaña-Loaiza, Omar S., Mirhosseini, Mohammad, Rodenburg, Brandon, Taherirostami, Payam   +5 more
core   +3 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Genotyping Single Nucleotide Polymorphisms Using Different Molecular Beacon Multiplexed within a Suspended Core Optical Fiber

Sensors, 2014
We report a novel approach to genotyping single nucleotide polymorphisms (SNPs) using molecular beacons in conjunction with a suspended core optical fiber (SCF).
Linh Viet Nguyen, Sara Giannetti, Stephen Warren-Smith, Alan Cooper, Stefano Selleri, Annamaria Cucinotta, Tanya Monro   +6 more
doaj   +1 more source

A Parallelized Nanofluidic Device for High-Throughput Optical DNA Mapping of Bacterial Plasmids

Micromachines, 2021
Optical DNA mapping (ODM) has developed into an important technique for DNA analysis, where single DNA molecules are sequence-specifically labeled and stretched, for example, in nanofluidic channels.
Sriram KK, Yii-Lih Lin, Tsegaye Sewunet, Marie Wrande, Linus Sandegren, Christian G. Giske, Fredrik Westerlund   +6 more
doaj   +1 more source

Direct fiber vector eigenmode multiplexing transmission seeded by integrated optical vortex emitters [PDF]

, 2017
Spatial modes have received substantial attention over the last decades and are used in optical communication applications. In fiber-optic communications, the employed linearly polarized modes and phase vortex modes carrying orbital angular momentum can ...
Cai, Xin-Lun, Chen, Shi, Du, Cheng, Klitis, Charalambos, Li, Shi-Mao, Liu, Jun, Mo, Qi, Sorel, Marc, Wang, An-Dong, Wang, Jian, Yu, Si-Yuan, Zhu, Long   +11 more
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

N-Acetyltyrosine as a Biomarker of Parenteral Nutrition Administration in First-Tier Newborn Screening Assays

International Journal of Neonatal Screening
Parenteral nutrition (PN) is a nutrient solution administered intravenously (IV) to premature babies. PN causes elevations of some amino acids in blood samples that are also biomarkers used in newborn screening (NBS).
C. Austin Pickens, Samyukta Sah, Rahul Chandrappa, Samantha L. Isenberg, Elya R. Courtney, Timothy Lim, Donald H. Chace, Rachel Lee, Carla Cuthbert, Konstantinos Petritis   +9 more
doaj   +1 more source

Novel Tetraplex Quantitative PCR Assays for Simultaneous Detection and Identification of Xylella fastidiosa Subspecies in Plant Tissues

Frontiers in Plant Science, 2019
Xylella fastidiosa (Xf) is an insect-borne bacterium confined to the xylem vessels of plants. This plant pathogen has a broad host range estimated to 560 plant species.
Enora Dupas, Enora Dupas, Martial Briand, Marie-Agnès Jacques, Sophie Cesbron   +4 more
doaj   +1 more source

Compendium of Plant-Specific CRISPR Vectors and Their Technical Advantages

Life, 2021
CRISPR/Cas mediated genome editing is a revolutionary approach for manipulating the plant genome. However, the success of this technology is highly dependent on selection of a specific vector and the other components.
Anshu Alok, Hanny Chauhan, Santosh Kumar Upadhyay, Ashutosh Pandey, Jitendra Kumar, Kashmir Singh   +5 more
doaj   +1 more source