Results 51 to 60 of about 217,867 (294)

High performance architecture design for large scale fibre-optic sensor arrays using distributed EDFAs and hybrid TDM/DWDM

, 2013
A distributed amplified dense wavelength division multiplexing (DWDM) array architecture is presented for interferometric fibre optic sensor array systems. This architecture employs a distributed erbium doped fibre amplifier (EDFA) scheme to decrease the
Austin, E.A., Kingsley, S.A., Liao, Y., Nash, P.J., Richardson, D.J.   +4 more
core   +1 more source

Novel Method for Improving the Capacity of Optical MIMO System Using MGDM [PDF]

, 2014
In current local area networks, multimode fibers (MMFs), primarily graded index (GI) MMFs, are the main types of fibers employed for data communications.
Aggoun, A., Attia, R., Baklouti, F., Dayoub, I., Haxha, Shyqyri   +4 more
core   +6 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Acquisition of Neural Action Potentials Using Rapid Multiplexing Directly at the Electrodes

Micromachines, 2018
Neural recording systems that interface with implanted microelectrodes are used extensively in experimental neuroscience and neural engineering research.
Mohit Sharma, Avery Tye Gardner, Hunter J. Strathman, David J. Warren, Jason Silver, Ross M. Walker   +5 more
doaj   +1 more source

Multiplexed Passive Optical Fiber Sensor Networks for Water Level Monitoring: A Review

Sensors, 2020
Water management is a critical mission required to protect the water resources that is essential in diverse industrial applications. Amongst a variety of parameters such as level (or depth), temperature, conductivity, turbidity, and pH, the water level ...
Hoon-Keun Lee, Jaeyul Choo, Joonyoung Kim   +2 more
doaj   +1 more source

Recent Advances in Field Effect Transistor Biosensors: Designing Strategies and Applications for Sensitive Assay

Biosensors, 2023
In comparison with traditional clinical diagnosis methods, field–effect transistor (FET)–based biosensors have the advantages of fast response, easy miniaturization and integration for high–throughput screening, which demonstrates their great technical ...
Ruisha Hao, Lei Liu, Jiangyan Yuan, Lingli Wu, Shengbin Lei   +4 more
doaj   +1 more source

Multiplexing oscillatory biochemical signals [PDF]

, 2013
In recent years it is increasingly being recognized that biochemical signals are not necessarily constant in time and that the temporal dynamics of a signal can be the information carrier.
de Ronde, Wiet, Wolde, Pieter Rein ten
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Multiplex engineering using microRNA-mediated gene silencing in CAR T cells

Frontiers in Immunology
BackgroundMultiplex gene-edited chimeric antigen receptor (CAR) T-cell therapies face significant challenges, including potential oncogenic risks associated with double-strand DNA breaks.
Giulia Golinelli, Giulia Golinelli, John Scholler, Audrey Roussel-Gervais, Antonija Šakić, Sten Ilmjärv, Decheng Song, Khatuna Gabunia, Mei Ji, Ting J. Fan, Aasha Gupta, Mansi Deshmukh, Abdulla Berjis, Abdulla Berjis, Riccardo Cuoghi Costantini, Kimberly Apodaca, Neil C. Sheppard, Sven Kili, Massimo Dominici, Marco Alessandrini, Carl H. June, Carl H. June, Carl H. June, Bruce L. Levine   +23 more
doaj   +1 more source

Multiplexed Nanobiosensors: Current Trends in Early Diagnostics

Sensors, 2020
The ever-growing demand for fast, cheap, and reliable diagnostic tools for personalised medicine is encouraging scientists to improve existing technology platforms and to create new methods for the detection and quantification of biomarkers of clinical ...
Greta Jarockyte, Vitalijus Karabanovas, Ricardas Rotomskis, Ali Mobasheri   +3 more
doaj   +1 more source