Results 41 to 50 of about 57,287 (266)
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Acquisition of Neural Action Potentials Using Rapid Multiplexing Directly at the Electrodes
Micromachines, 2018 Neural recording systems that interface with implanted microelectrodes are used extensively in experimental neuroscience and neural engineering research.
Mohit Sharma +5 more
doaj +1 more source
Multiplexed Passive Optical Fiber Sensor Networks for Water Level Monitoring: A Review
Sensors, 2020 Water management is a critical mission required to protect the water resources that is essential in diverse industrial applications. Amongst a variety of parameters such as level (or depth), temperature, conductivity, turbidity, and pH, the water level ...
Hoon-Keun Lee +2 more
doaj +1 more source
BioTechniques, 2021 The ongoing pandemic has demonstrated the utility of widespread surveillance and diagnostic detection of the novel SARS-CoV-2. Reverse-transcription loop-mediated isothermal amplification (RT-LAMP) has enabled broader testing, but current LAMP tests only
Yinhua Zhang, Nathan A Tanner
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Multiplex engineering using microRNA-mediated gene silencing in CAR T cells
Frontiers in ImmunologyBackgroundMultiplex gene-edited chimeric antigen receptor (CAR) T-cell therapies face significant challenges, including potential oncogenic risks associated with double-strand DNA breaks.
Giulia Golinelli +23 more
doaj +1 more source
Multiplexed Nanobiosensors: Current Trends in Early Diagnostics
Sensors, 2020 The ever-growing demand for fast, cheap, and reliable diagnostic tools for personalised medicine is encouraging scientists to improve existing technology platforms and to create new methods for the detection and quantification of biomarkers of clinical ...
Greta Jarockyte +3 more
doaj +1 more source
Proteomics applications in biomedical research and diagnosis by luminex in Egypt [PDF]
Egyptian Journal of Cancer and Biomedical Research, 2018 To accurate prognosis, diagnosis and treatment for several diseases such as cancer, diabetes and autoimmune diseases, the results of analysis should be accurate with high precision.
Sabry El-Naggar +9 more
doaj +1 more source