Results 81 to 90 of about 296,891 (323)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Orthogonal Chirp Division Multiplexing

open access: yes, 2016
Chirp waveform plays a significant role in radar and communication systems for its ability of pulse compression and spread spectrum. This paper presents a principle of orthogonally multiplexing a bank of linear chirp waveforms within the same bandwidth ...
Ouyang, Xing, Zhao, Jian
core   +1 more source

Time domain multiplexed spatial division multiplexing receiver

open access: yesOptics Express, 2014
A novel time domain multiplexed (TDM) spatial division multiplexing (SDM) receiver which allows for the reception of >1 dual polarization mode with a single coherent receiver, and corresponding 4-port oscilloscope, is experimentally demonstrated. Received by two coherent receivers and respective 4-port oscilloscopes, a 3 mode transmission of 28GBaud ...
Uden, van, R.G.H.   +4 more
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

A Multi-Channel Asynchronous Neurostimulator With Artifact Suppression for Neural Code-Based Stimulations

open access: yesFrontiers in Neuroscience, 2019
A novel neurostimulator for generating neural code-based, precise, asynchronous electrical stimulation pulses is designed, fabricated, and characterized.
Sahar Elyahoodayan   +4 more
doaj   +1 more source

Method for holographic storage using peristrophic multiplexing [PDF]

open access: yes, 1994
A method of multiplexing holograms by rotating the material or, equivalently, the recording beams is described. Peristropic (Greek for rotation) multiplexing can be combined with other multiplexing methods to increase the storage density of holographic ...
Curtis, Kevin   +2 more
core  

Fundamental Limits in Correlated Fading MIMO Broadcast Channels: Benefits of Transmit Correlation Diversity

open access: yes, 2014
We investigate asymptotic capacity limits of the Gaussian MIMO broadcast channel (BC) with spatially correlated fading to understand when and how much transmit correlation helps the capacity.
Nam, Junyoung
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Diversity Order Gain with Noisy Feedback in Multiple Access Channels

open access: yes, 2008
In this paper, we study the effect of feedback channel noise on the diversity-multiplexing tradeoff in multiuser MIMO systems using quantized feedback, where each user has m transmit antennas and the base-station receiver has n antennas.
Aggarwal, Vaneet, Sabharwal, Ashutosh
core   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy