Results 41 to 50 of about 10,154 (314)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

On Similarity and Reducing Subspaces of the n-Shift plus Certain Weighted Volterra Operator

Journal of Function Spaces, 2017
Let g(z) be an n-degree polynomial (n≥2). Inspired by Sarason’s result, we introduce the operator T1 defined by the multiplication operator Mg plus the weighted Volterra operator Vg on the Bergman space.
Yucheng Li, Hao Chen, Wenhua Lan
doaj   +1 more source

Multiplication operators on the Banach algebra of bounded Φ-variation functions on compact subsets of ℂ

Demonstratio Mathematica, 2022
Let AΦ(K){{\mathbb{A}}}_{\Phi }\left({\bf{K}}) be the Banach algebra of bounded Φ\Phi -variation functions defined on a compact set K{\bf{K}} in the complex plane, hh a function defined on K{\bf{K}}, and Mh{M}_{h} a multiplication operator induced by hh.
Bracamonte Mireya, Ereú Jurancy, Marchan Luz   +2 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Chaotic roots of the modular multiplication dynamical system in Shor's algorithm

Physical Review Research
Shor's factoring algorithm, believed to provide an exponential speedup over classical computation, relies on finding the period of an exactly periodic quantum modular multiplication operator. This exact periodicity is the hallmark of an integrable system,
Abu Musa Patoary, Amit Vikram, Laura Shou, Victor Galitski   +3 more
doaj   +1 more source

Boundedness and compactness of a new product-type operator from a general space to Bloch-type spaces

Journal of Inequalities and Applications, 2016
We characterize the boundedness and compactness of a product-type operator, which, among others, includes all the products of the single composition, multiplication, and differentiation operators, from a general space to Bloch-type spaces.
Stevo Stević, Ajay K Sharma, Ram Krishan   +2 more
doaj   +1 more source

A note on Nakano generalized difference sequence space

Advances in Difference Equations, 2020
In this paper, we investigate the necessary conditions on any s-type sequence space to form an operator ideal. As a result, we show that the s-type Nakano generalized difference sequence space X fails to generate an operator ideal.
Awad A. Bakery, Afaf R. Abou Elmatty
doaj   +1 more source

On a Sum of More Complex Product-Type Operators from Bloch-Type Spaces to the Weighted-Type Spaces

Axioms, 2023
The aim of the present paper is to completely characterize the boundedness and compactness of a sum operator defined by some more complex products of composition, multiplication, and mth iterated radial derivative operators from Bloch-type spaces to ...
Cheng-Shi Huang, Zhi-Jie Jiang
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Characterizations of the product of asymmetric dual truncated Toeplitz operators

AIMS Mathematics
The asymmetric dual truncated Toeplitz operator (ADTTO) is a compression multiplication operator acting on the orthogonal complement of two different model spaces.
Zhenhui Zhu, Qi Wu, Yong Chen
doaj   +1 more source