Results 41 to 50 of about 1,749 (282)

Analyzing Diabetic Dynamics with MRK4, and LSTM Techniques with Multiplicative Calculus

open access: yesCumhuriyet Science Journal
This study compares the use of Long Short-Term Memory (LSTM) networks for predictive modeling with multiplicative calculus. We evaluate and quantitatively analyze both methodologies to determine their prediction performance.
Bugce Eminaga Tatlicioglu
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

On a Non-Newtonian Calculus of Variations

open access: yesAxioms, 2021
The calculus of variations is a field of mathematical analysis born in 1687 with Newton’s problem of minimal resistance, which is concerned with the maxima or minima of integral functionals.
Delfim F. M. Torres
doaj   +1 more source

On Multiplicity-Free Skew Characters and the Schubert Calculus [PDF]

open access: yesAnnals of Combinatorics, 2010
In this paper we classify the multiplicity-free skew characters of the symmetric group. Furthermore we show that the Schubert calculus is equivalent to that of skew characters in the following sense: If we decompose the product of two Schubert classes we get the same as if we decompose a skew character and replace the irreducible characters by Schubert
openaire   +3 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Milne's Estimates via Conformable Fractional Multiplicative Integrals

open access: yesUniversal Journal of Mathematics and Applications
This paper explores Milne’s inequality in the context of multiplicative conformable fractional integrals, a recent extension of classical fractional calculus rooted in non-Newtonian analysis.
Abdelghani Lakhdari   +3 more
doaj   +1 more source

Complex Multiplicative Calculus

open access: yes, 2011
In the present paper we extend the concepts of multiplicative de- rivative and integral to complex-valued functions of complex variable. Some drawbacks, arising with these concepts in the real case, are explained satis- factorily. Properties of complex multiplicative derivatives and integrals are studied.
Bashirov, Agamirza, Riza, Mustafa
openaire   +2 more sources

The Multiplicative-Additive Lambek Calculus with Subexponential and Bracket Modalities [PDF]

open access: yesJournal of Logic, Language and Information, 2020
Accepted for publication in the Journal of Logic, Language, and ...
Max I. Kanovich   +2 more
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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