Results 61 to 70 of about 1,749 (282)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Multiplicative finite difference methods

, 2009
Based on multiplicative calculus, the finite difference schemes for the numerical solution of multiplicative differential equations and Volterra differential equations are presented. Sample problems were solved using these new approaches.
Özyapici A., Misirli E., Riza M.
core   +2 more sources

Probabilistic study of a dynamical system [PDF]

, 2000
This paper investigates the relation between a branching process and a non-linear dynamical system in C2. This idea has previously been fruitful in many investigations, including that of the FKPP equation by McKean, Neveu, Bramson, and others.
Warren, Jon, Williams, D.
core   +1 more source

Fractional integral inequalities for strongly convex functions via multiplicative calculus with applications

Boundary Value Problems
In this paper, we introduce the concept of strongly multiplicative convex functions and establish Hermite–Hadamard (HH)-type integral inequalities using the Atangana–Baleanu (AB) fractional integral operator within the framework of multiplicative ...
Saad Ihsan Butt, Dawood Khan, Valer-Daniel Breaz, Luminita-Ioana Cotîrlǎ, Bandar Bin Mohsin   +4 more
doaj   +1 more source

Characterizing Behavioural Congruences for Petri Nets

, 1995
We exploit a notion of interface for Petri nets in order to design a set of net combinators. For such a calculus of nets, we focus on the behavioural congruences arising from four simple notions of behaviour, viz., traces, maximal traces, step, and ...
Priese, L., Nielsen, M., Lutz Priese, Vladimiro Sassone, Sassone, V., Mogens Nielsen   +5 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

q-Multiplicative Dirac System [PDF]

, 2023
In this study, the classical Dirac equation was investigated on the basis of q-multiplicative calculus. We discuss some spectral properties of the q-multiplicative Dirac system, such as formally self-adjointness, and orthogonality of eigenfunctions ...
Allahverdiev, Bilender P., Tuna, Huseyin
core  

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

On modeling with multiplicative differential equations

, 2011
This work is aimed to show that various problems from different fields can be modeled more efficiently using multiplicative calculus, in place of Newtonian calculus. Since multiplicative calculus is still in its infancy, some effort is put to explain its
Tandogdu, Yucel, Bashirov, Agamirza E., Ozyapici, Ali, Misirli, Emine   +3 more
core   +1 more source