Results 31 to 40 of about 36,760 (266)
Additive and multiplicative hazards modeling for recurrent event data analysis
BMC Medical Research Methodology, 2011 Background Sequentially ordered multivariate failure time or recurrent event duration data are commonly observed in biomedical longitudinal studies. In general, standard hazard regression methods cannot be applied because of correlation between recurrent
Zhang Xu, Lim Hyun J
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Ordering the Multiple Pathways of Apoptosis
Trends in Cardiovascular Medicine, 1997 Apoptosis plays an important role in development, homeostasis, and disease. Current work has suggested that apoptosis can be evoked by multiple stimuli that, in turn, initiate distinct death pathways. Recently, exciting advances have been made in the understanding of biochemical pathways that regulate apoptotic processes.
D S, Park, L, Stefanis, L A, Greene
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Multiple-order singularity expansion method
New Journal of Physics, 2023 Abstract Physical systems and signals are characterized by complex functions of the frequency in the harmonic domain. The extension of such functions to the complex frequency plane, and in particular expansions and factorized forms of the harmonic-domain functions in terms of their poles and zeros, is of high interest to describe the ...
Ben Soltane, I +4 more
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FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
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A product autoregressive model with log-Laplace marginal distribution
Statistica, 2013 The log-Laplace distribution and its properties are considered. Some important properties like multiplicative infinite divisibility, geometric multiplicative infinite divisibility and self-decomposability are discussed.
Kanichukattu K. Jose, Manu Mariam Thomas
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Birth order and multiple sclerosis
Acta Neurologica Scandinavica, 2009 A correlation has been reported between the development of MS and sibling birth order. We have re-examined the question in 2 groups of MS families. The first group consisted of 175 MS patients from single affected families. The second consisted of 36 families in which 2 or more sibs in the family had MS.
Cripps, J, Rudd, A, Ebers, G
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
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PERIODIC AND ALMOST-PERIODIC SOLUTIONS OF RECURRENT MULTIPLICATIVE SECOND-ORDER EQUATIONS
Современная наука и инновации, 2022 Solutions of the recurrent multiplicative equation of a special kind are considered. The values of the parameters of the equation are defined, for which the solutions are periodic, almost periodic or combine properties of a geometric progression and ...
Victor Grigorievich Rudenko +2 more
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