Bounds of Gelfand-Tsetlin multiplicities and tableaux realizations of Verma modules
Vyacheslav Futorny
openalex +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Numerical construction of structured matrices with given eigenvalues
We consider a structured inverse eigenvalue problem in which the eigenvalues of a real symmetric matrix are specified and selected entries may be constrained to take specific numerical values or to be nonzero.
Sutton Brian D.
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Multiplicity and asymptotics of positive normalized solutions for the fractional Sobolev critical Schr\"{o}dinger equations [PDF]
Lingzheng Kong, Haibo Chen
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Who Is the Customer? On Multiple-Customer Representation in Supply Chains
Background: Customer orders are key in developing logistics processes and in strategic developments of customer orientation. This paper investigates the notion of customer orientation.
Benedikte Borgström +2 more
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Soft multiple parton interactions as seen in multiplicity distributions at Tevatron and LHC [PDF]
Igor Dremin, V. A. Nechitaǐlo
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This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Positive Solutions to a System of Coupled Hadamard Fractional Boundary Value Problems
We explore the existence, uniqueness, and multiplicity of positive solutions to a system of Hadamard fractional differential equations that contain fractional integral terms.
Alexandru Tudorache, Rodica Luca
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

