Results 221 to 230 of about 312,350 (315)

Multiplicity and complexity issues in contemporary production scheduling.

Klundert, J. van de, Grigoriev, A., Crama, Y., Brauner, N   +3 more
core   +2 more sources

Combined Experimental and Computational Study on the Structure-Property Relationships of Mono- and Dicationic Imidazolium Ionic Liquids for CO₂ Capture. [PDF]

J Phys Chem B
Duarte E, Forneck V, Motta E, Dos Santos L, Andreeva NA, Chaban VV, Bernard FL, Einloft S.   +7 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Long-Term Efficacy of Arthroscopic Microfracture Combined With Autologous Collagen-Induced Chondrogenesis for Knee Cartilage Defects: A 5-Year Prospective Pilot Randomized Controlled Trial. [PDF]

Orthop Surg
Ren S, Bai Z, Lu X, Zhang Y, Sun X, Tang R, Yang B, Qian J, Qiu G.   +8 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Association of Breast Tissue Composition on Preoperative Automated Breast Ultrasound With Accuracy of Cancer Multiplicity Evaluation and Recurrence-Free Survival in Patients With Early-Stage Breast Cancer. [PDF]

Korean J Radiol
Kim MK, Kim H, Baek SY, Ko EY, Han BK, Ko ES, Lee J, Choi N, Chung J, Choi JS.   +9 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The immunoproteome and multimorbidity: A Mendelian randomization study. [PDF]

Sci Adv
Hukerikar N, Hingorani AD, Chopade S, Cupido AJ, Asselbergs FW, Finan C, Schmidt AF.   +6 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Identification of susceptibility loci using a novel murine model for triple-negative breast cancer. [PDF]

G3 (Bethesda)
Kim M, McGrath LG, Mustafa ZT, Eugin Simon S, Pervaiz N, Grey EW, Joseph SC, Korba E, Marathe SJ, Bohm MS, Ramesh AV, Mahajan SS, Bohl CJ, Prins P, Read RW, Holt JR, Hayes DN, Lu L, Williams RW, Sipe LM, Ashbrook DG, Makowski L.   +21 more
europepmc   +1 more source