Results 61 to 70 of about 2,030,812 (333)
On Theoretical Incomprehensibility
Philosophies, 2019 This contribution tentatively outlines the presumed conceptual duality between the issues of incompleteness and incomprehensibility—The first being more formal in nature and able to be declined in various ways until specified in the literature as ...
Gianfranco Minati
doaj +1 more source
Phage therapy dosing: The problem(s) with multiplicity of infection (MOI)
Bacteriophage, 2016 The concept of bacteriophage multiplicity of infection (MOI) – ratios of phages to bacteria – historically has been less easily applied than many phage workers would prefer or, perhaps, may be aware.
S. Abedon
semanticscholar +1 more source
Approximation Algorithms for Covering/Packing Integer Programs [PDF]
, 2005 Given matrices A and B and vectors a, b, c and d, all with non-negative entries, we consider the problem of computing min {c.x: x in Z^n_+, Ax > a, Bx < b, x < d}.
Balas +27 more
core +4 more sources
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Carlo Rovelli, L’ordine del tempo
Techne, 2020 Carlo Rovelli’s book is a journey through time and space that brings us to the essence of the human being and, I would like to say, of the technological man who lives in us.
Alessandra Zanelli
doaj +1 more source
An Evolutionary Argument for a Self-Explanatory, Benevolent Metaphysics [PDF]
, 2015 In this paper, a metaphysics is proposed that includes everything that can be represented by a well-founded multiset. It is shown that this metaphysics, apart from being self-explanatory, is also benevolent.
Blondé, Ward
core +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
A priori bounds and multiplicity of positive solutions for p-Laplacian Neumann problems with sub-critical growth [PDF]
Proceedings of the Royal Society of Edinburgh: Section A Mathematics, 2018 Let 1 < p < +∞ and let Ω ⊂ ℝN be either a ball or an annulus. We continue the analysis started in [Boscaggin, Colasuonno, Noris, ESAIM Control Optim. Calc. Var. (2017)], concerning quasilinear Neumann problems of the type $-\Delta _pu = f(u),\quad u > 0\,
A. Boscaggin +2 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley +1 more source