Results 31 to 40 of about 37,386 (261)

USING INPUT-OUTPUT ANALYSIS APPROACH TO IDENTIFY THE ROLE OF AGRICULTURAL SECTORS IN JAMBI ECONOMY [PDF]

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2019
This study aims to analyze the linkages of agriculture sector to other sectors of the economy of Jambi Province and also to know the multiplier output and export multiplier of the agricultural sector. The agricultural sector which in fact is the dominant
Fitri Y., Amir A., Murdi S., Syafaruddin
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Hermite multipliers and pseudo-multipliers [PDF]

open access: yesProceedings of the American Mathematical Society, 1996
We prove a multiplier theorem for the Hermite-Triebel-Lizorkin spaces introduced by Epperson in [Studia Math. 114 (1995), 87–103]. This extends Thangavelu’s theorem [Revist. Mat. Ibero 3 (1987), 1–24; Math. Notes, vol. 42, 1993] on Hermite multipliers for L p L^p spaces. We also prove an L p
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Multipliers

open access: yesFilomat, 2013
We describe the multiplier spaces (Hp,q,?,H?), and (Hp,q,?,H?,v,?), where Hp,q,? are mixed norm spaces of analytic functions in the unit disk D and H? is the space of bounded analytic functions in D. We extend some results from [7] and [3], particularly Theorem 4.3 in [3].
Emily Moore, Harriet Pollatsek
openaire   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Theory of J. M. Keynes as a revolutionary approach to economics.

open access: yesХабаршысы. Экономика сериясы, 2016
In 2016 been celebrated the 80th anniversary of publication of the work of Keynes’ «General Theory of Employment, Interest and Money». This date are updated by exploration of the phenomenon of labor, forces to search for the answer to the question about ...
B. Z. Nurmanova
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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