Results 51 to 60 of about 3,648 (209)

SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition

Advanced Science, EarlyView.
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang, Jingyi Xu, Yonghong Wu, Yitong Qu, Xinglin Hu, Yuchen Sun, Yanshuang Wu, Zhonghua Liu, Jiaqiang Wang, Lei Lei   +9 more
wiley   +1 more source

Theoretical Aspects of the Study of Problems of BRICS Countries Cooperation

Сравнительная политика, 2016
The article deals with the problems and prospects of mutual cooperation between the countries-members of BRICS in the light of contemporary processes of globalization and the restructuring of the global political and economic system.
A. A. Konkin
doaj   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

Mapping multipolarity: soft and hard power in the digital age

Discover Global Society
This paper examines how “multipolarity” is framed across digital and academic venues and how these framings may relate to soft- and hard-power narratives.
Ana Rodica Stăiculescu, Emanuela Bran, Andra Seceleanu, Aurel Papari   +3 more
doaj   +1 more source

Strategic Partnership between Russia and China: Importance and Sustainability of Bilateral Relations

Сравнительная политика, 2016
In the light of the present political situation in the world, namely complex relations between Russia and the West, on the one hand, and existing tensions between China and some of its regional neighbors, on the other, strategic partnership between ...
A. V. Sharyshev
doaj   +1 more source

Automating Sustainability: How Climate Action Unlocks the ESG Potential of Industrial Robotics

Business Strategy and the Environment, EarlyView.
ABSTRACT The convergence of Industry 4.0 and global sustainability goals presents a critical paradox: while automation drives efficiency, its net impact on comprehensive environmental, social, and governance (ESG) performance remains contested. This study investigates the relationship between industrial robot and country‐level ESG performance across 63
Brahim Bergougui
wiley   +1 more source

Determination and Recovery of Spin‐States for a High‐Spin and a Spin‐Crossover Complex by Means of X‐Ray Wavefunction Refinement

Chemistry – A European Journal, EarlyView.
The determination of spin‐states by methods like Hirshfeld atom refinement is a promising development in the field of quantum crystallography. To this end, we present x‐ray wavefunction refinement as a next step in this process, identifying the spin and translating it into a physical wavefunction.
Johannes Bartusel, Daniel Brüx, Christoph Hennig, Florian Kleemiss   +3 more
wiley   +1 more source

Africa, from globalization to unstable multipolarity [PDF]

O artigo analisa a transição africana, no plano internacional, da inserção na globalização neoliberal ao protagonismo na Multipolaridade Instável. Destaca que, apesar das dificuldades impostas pela globalização neoliberal, ela permitiu que a África ...
Vizentini, Paulo Gilberto Fagundes
core   +1 more source

Rethinking the Rise of China and Its Implications on International Order

Chinese Journal of International Review, 2020
The rise of China has become a central debate in the academic field of international relations. In the Western world, the scholars within this debate can roughly be divided into the ‘pessimists’ and the ‘optimists’.
Ciwan M. Can, Anson Chan
doaj   +1 more source

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter‐compatible endovascular electroencephalogram electrode: A clinical feasibility trial

Epilepsia Open, EarlyView.
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki, Yosuke Masuda, Ayataka Fujimoto, Mitsuyo Nishimura, Hisayuki Hosoo, Hiroki Ishida, Takashi Enokizono, Kensuke Kawai, Eiichi Ishikawa, Yuji Matsumaru   +9 more
wiley   +1 more source