Results 151 to 160 of about 60,202 (192)

The many faces of the GID/CTLH E3 ligase complex. [PDF]

open access: yesBiochem Soc Trans
Alpi AF   +3 more
europepmc   +1 more source

C6orf223 promotes colorectal cancer growth and metastasis by facilitating PRMT5-MEP50 multiprotein complex assembling. [PDF]

open access: yesJ Clin Invest
Qiao Y   +20 more
europepmc   +1 more source
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ACEMBLing a Multiprotein Transmembrane Complex

Nature Methods, 2015
Structural and functional studies of many multiprotein complexes depend on recombinant-protein overexpression. Rapid revision of expression experiments and diversification of the complexes are often crucial for success of these projects; therefore, automation is increasingly indispensable.
Joanna Komar   +4 more
openaire   +4 more sources

Multiprotein complexes governing Wnt signal transduction

Current Opinion in Cell Biology, 2018
Three multiprotein complexes have key roles in transducing Wnt signals from the plasma membrane to the cell nucleus - the β-catenin destruction complex, or Axin degradasome, which targets the Wnt effector β-catenin for proteasomal degradation in the absence of Wnt; the Wnt signalosome, assembled by polymerization of Dishevelled upon Wnt engaging its ...
Melissa, Gammons, Mariann, Bienz
openaire   +2 more sources

Multiprotein complex signaling and the plasticity problem

Current Opinion in Neurobiology, 2001
Synaptic transmission of distinct patterns of spikes, or 'neural code', leads to plastic changes in synapses and other parts of the neuron, as well as learning in animals. Recent findings indicate that specialized multiprotein structures associated with neurotransmitter receptors and cell-adhesion proteins function as molecular devices that both read ...
S G, Grant, T J, O'Dell
openaire   +2 more sources

Baculovirus expression system for heterologous multiprotein complexes

Nature Biotechnology, 2004
The discovery of large multiprotein complexes in cells has increased the demand for improved heterologous protein production techniques to study their molecular structure and function. Here we describe MultiBac, a simple and versatile system for generating recombinant baculovirus DNA to express protein complexes comprising many subunits.
Imre, Berger   +2 more
openaire   +2 more sources

MULTIPROTEIN-DNA COMPLEXES IN TRANSCRIPTIONAL REGULATION

Annual Review of Biophysics and Biomolecular Structure, 1999
▪ Abstract  Transcription in eukaryotes is frequently regulated by a mechanism termed combinatorial control, whereby several different proteins must bind DNA in concert to achieve appropriate regulation of the downstream gene. X-ray crystallographic studies of multiprotein complexes bound to DNA have been carried out to investigate the molecular ...
openaire   +2 more sources

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