Solving the binding problem: cellular adhesive molecules and their control of the cortical quantum entangled network [PDF]
, 2003 Quantum entanglement is shown to be the only acceptable physical solution to the binding problem. The biological basis of interneuronal entanglement is described in the frames of the beta-neurexin-neuroligin model developed by Georgiev (2002) and is ...
Georgiev, Danko
core
British Journal of Pharmacology, Volume 183, Issue 11, Page 3111-3128, June 2026.Abstract Background and Purpose Alcohol abuse and affective disorders are severe comorbid psychiatric diseases characterized by impaired brain synaptic transmission. The role of presynaptic scaffolding proteins coordinating presynaptic plasticity and neurotransmitter release, such as Bassoon (Bsn), in the pathogenesis of these disorders remains elusive.
Liubov S. Kalinichenko +14 more
wiley +1 more source
Author Correction: HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system. [PDF]
Sci Rep, 2022 Kolesnikova O +11 more
europepmc +1 more source
A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling. [PDF]
, 2018 Detection of viral genomes by the innate immune system elicits an antiviral gene program mediated by type I interferons (IFNs). While viral RNA and DNA species induce IFN via separate pathways, the mechanisms by which these pathways are differentially ...
Aliyari, Saba Roghiyh +9 more
core
Efficiency of energy funneling in the photosystem II supercomplex of higher plants
, 2015 The investigation of energy transfer properties in photosynthetic multi-protein networks gives insight into their underlying design principles.Here, we discuss excitonic energy transfer mechanisms of the photosystem II (PS-II) C$_2$S$_2$M$_2 ...
Aspuru-Guzik, Alán +1 more
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The FASEB Journal, Volume 40, Issue 9, 15 May 2026.Proposed signaling pathway by which TY modulates NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis. ABSTRACT This research focuses on exploring the modulation of pyroptosis and its underlying mechanisms via the “Tianyu” formulation (TY), a traditional Chinese medicine, in human rheumatoid arthritis fibroblast‐like synovial cells (RA‐HFLS) and a collagen ...
Yueya Zhu +5 more
wiley +1 more source
The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth
Frontiers in Cell and Developmental Biology, 2017 Cell size is amenable by genetic and environmental factors. The highly conserved nutrient-responsive Target of Rapamycin (TOR) signaling pathway regulates cellular metabolic status and growth in response to numerous inputs.
Suam Gonzalez, Charalampos Rallis
doaj +1 more source
High‐Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor
MedComm, Volume 7, Issue 5, May 2026.We conducted a high‐throughput screen of 2747 FDA‐approved drugs to identify inhibitors of pyroptosis. We found that CeeNU significantly repressed NLRP3‐dependent IL‐1β release and GSDMD pore‐forming complex. We identified that the arginine 335 amino acid of the NACHT domain of NLRP3 is the critical point for human NLRP3 and CeeNU interaction and ...
Sen‐Lin Ji +11 more
wiley +1 more source
Inflammasome — a new look at the therapy of cardiovascular diseases. Part II
Российский кардиологический журналThe role of inflammasomes in cardiovascular diseases has not been sufficiently studied at present. However, there are a number of recent studies showing the participation of these multiprotein complexes in the development and progression of ...
A. A. Rubinstein +5 more
doaj +1 more source
Dynamics of chromatin structure and nuclear multiprotein complexes investigated by quantitative fluorescence live cell microscopy and computational modeling [PDF]
, 2009 Norman Constantin Kappel
openalex +1 more source