Results 151 to 160 of about 960,142 (193)

New methodologies in native mass spectrometry and ion mobility for the structural characterization of proteins of therapeutic interest and multiprotein complexes

open access: yes, 2019
Ce travail de thèse repose sur le développement de méthodes en spectrométrie de masse native et mobilité ionique pour la caractérisation structurale de protéines d’intérêt thérapeutique et de complexes multiprotéiques.
Botzanowski, Thomas
core  

Protein–Protein Interactions Between Peptidoglycan, Lipopolysaccharide, and Phospholipid Biosynthesis Enzymes in Escherichia coli

open access: yesChemBioChem, Volume 27, Issue 16, 27 August 2026.
MurA, the first peptidoglycan biosynthesis enzyme, interacts with essential proteins involved in lipopolysaccharide and phospholipid biogenesis and is associated with the LapB interactome. Gram‐negative bacteria are protected by a three‐layered cell envelope and must tightly coordinate the biosynthesis of phospholipids (PL), peptidoglycan (PG) and ...
Lea‐Janina Tilg   +4 more
wiley   +1 more source

Selenoprotein S is involved in maintenance and transport of multiprotein complexes. [PDF]

open access: yesBiochem J, 2014
Turanov AA   +8 more
europepmc   +1 more source

Structure‐Guided Optimization of a Molecular Glue Targeting the KBTBD4‐HDAC1/2 Complex

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Structure‐based optimization of the molecular glue degrader UM171 resulted in a near 20‐fold improvement of ternary complex stability but also revealed the challenges of glue discovery. Optimization of UM171, a molecular glue initiating the degradation of neosubstrate HDAC1/2–CoREST–LSD1 through a multiprotein complex formed with KBTBD4, was carried ...
Timea Balo   +8 more
wiley   +1 more source

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