Regulatory roles of an atypical ubiquitin ligase UBE2O in orphans of multiprotein complexes for degradation. [PDF]
Turk J Biol, 2022 Lv Y, Xing F.
europepmc +1 more source
Studying multiprotein complexes by multisignal sedimentation velocity analytical ultracentrifugation
, 2005 Protein interactions can promote the reversible assembly of multiprotein complexes, which have been identified as critical elements in many regulatory processes in cells.
Mariuzza, Roy A. +5 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise +2 more
wiley +1 more source
Impact of Ferrous Sulfate on Thylakoidal Multiprotein Complexes, Metabolism and Defence of Brassica juncea L. under Arsenic Stress. [PDF]
Plants (Basel), 2022 Ali AA +5 more
europepmc +1 more source
Molecular architecture of meiotic multiprotein complexes
, 2020 Sich sexuell fortpflanzende Organismen sind auf die Meiose angewiesen, um haploide, genetisch vielfältige Keimzellen zu erzeugen, die die Stabilität des Genoms und die Fähigkeit zur Anpassung an sich verändernde Umgebungen erhalten. Die Haploidisierung wird durch zwei aufeinanderfolgende Runden der Zellteilung nach einer einzigen anfänglichen prä ...
openaire +2 more sources
Mass spectrometry proteomics for studying mitostasis
Protein Science, Volume 35, Issue 7, July 2026.Abstract Maintaining mitochondrial integrity and function is fundamental to cellular homeostasis. Cells rely on coordinated protein quality control (QC) systems—including intricate chaperone‐protease networks, the ubiquitin‐proteasome system, and cytosolic surveillance pathways—that together form a dynamic, cell‐wide mitostasis network governing the ...
Lakshita Sharma +5 more
wiley +1 more source
Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders
Journal of Immunology Research, 2016 Inflammasomes are multiprotein complexes that trigger the activation of caspases-1 and subsequently the maturation of proinflammatory cytokines interleukin-1β and interleukin-18.
Keren Zhou +4 more
doaj +1 more source
HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system. [PDF]
Sci Rep, 2022 Kolesnikova O +11 more
europepmc +1 more source
Acyl modification and binding of mitochondrial ACP to multiprotein complexes
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2017 The mitochondrial acyl carrier protein (ACPM/NDUFAB1) is a central element of the mitochondrial fatty acid synthesis type II machinery. Originally ACPM was detected as a subunit of respiratory complex I but the reason for the association with the large enzyme complex remained elusive.
Heike Angerer +9 more
openaire +3 more sources
Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation
European Journal of Haematology, Volume 117, Issue 1, Page 132-143, July 2026.ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese +12 more
wiley +1 more source