Results 201 to 210 of about 5,625 (248)

Moving Sum Procedure for Multiple Change Point Detection in Large Factor Models

open access: yesJournal of Time Series Analysis, EarlyView.
ABSTRACT This paper proposes a moving sum methodology for detecting multiple change points in high‐dimensional time series under a factor model, where changes are attributed to those in loadings as well as emergence or disappearance of factors. We establish the asymptotic null distribution of the proposed test for family‐wise error control and show the
Matteo Barigozzi   +2 more
wiley   +1 more source

Online Jump and Kink Detection in Segmented Linear Regression: Statistical Optimality Meets Computational Efficiency

open access: yesJournal of Time Series Analysis, EarlyView.
ABSTRACT We consider the problem of sequential (online) estimation of a single change point in a piecewise linear regression model under a Gaussian setup. We demonstrate that certain CUSUM‐type statistics attain the minimax optimal rates for localizing the change point.
Annika Hüselitz, Housen Li, Axel Munk
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

A Network‐Based Approach to Understanding Key Signaling Pathways in Intervertebral Disc Biology

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
A literature‐based signaling network capturing the most relevant pathways in human nucleus pulposus cells was first constructed from curated biological evidence. The network was then translated into a system of ordinary differential equations to derive steady‐state solutions and define median baseline activity levels.
Sofia Tseranidou   +11 more
wiley   +1 more source

Understanding Multiscale Lithium Transport Dynamics in Composite Si‐C Electrodes: An Asymptotic Framework for GITT Experiments

open access: yesBattery Energy, Volume 5, Issue 3, May 2026.
This study introduces an asymptotic analysis to elucidate the multi‐scale transport mechanisms driving the relaxation dynamics in GITT experiments on composite Si‐C/graphite electrodes. The approach not only enhances physical understanding of coupled lithium transport mechanisms but also establishes a base for redesigning GITT protocols to achieve more
E. Jane, M. Higuera, F. Varas
wiley   +1 more source

Heart Rate Variability in Newborns From Diabetic Mothers: Clinical Application and Significance

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
Risk factors for GDM contribute to a hyperglycemic intrauterine environment, which may in turn impair ANS function in the offspring. Altered ANS activity can be assessed through measures such as HRV. ABSTRACT Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications, arising from inadequate insulin secretion and increased ...
Virginia Beretta   +7 more
wiley   +1 more source

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