Results 81 to 90 of about 668,130 (171)

Imaging the small animal cardiovascular system in real-time with multispectral optoacoustic tomography.

, 2011
Multispectral Optoacoustic Tomography (MSOT) is an emerging technique for high resolution macroscopic imaging with optical and molecular contrast. We present cardiovascular imaging results from a multi-element real-time MSOT system recently developed for
Taruttis, A., Herzog, E., Razansky, D., Ntziachristos, V.   +3 more
core   +1 more source

Reporter gene-based optoacoustic imaging of E. coli targeted colon cancer in vivo

Scientific Reports, 2021
Bacteria-mediated cancer-targeted therapy is a novel experimental strategy for the treatment of cancers. Bacteria can be engineered to overcome a major challenge of existing therapeutics by differentiating between malignant and healthy tissue.
Misun Yun, Sung-Hwan You, Vu Hong Nguyen, Jaya Prakash, Sarah Glasl, Vipul Gujrati, Hyon E. Choy, Andre C. Stiel, Jung-Joon Min, Vasilis Ntziachristos   +9 more
doaj   +1 more source

Breaking (Light) Barriers: Photoacoustics in Atherosclerotic Diseases

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Photoacoustic imaging (PAI) is an emerging imaging modality that provides high‐resolution, spatiotemporal insights into anatomical structures, functional parameters and molecular characteristics of tissues. By leveraging both endogenous absorbers, such as lipids and collagen, and exogenous contrast agents like nanoparticles and molecular dyes,
Kayleigh van Dijk, Margreet R. de Vries
wiley   +1 more source

Multimodal cell tracking from systemic administration to tumour growth by combining gold nanorods and reporter genes

eLife, 2018
Understanding the fate of exogenous cells after implantation is important for clinical applications. Preclinical studies allow imaging of cell location and survival.
Joan Comenge, Jack Sharkey, Oihane Fragueiro, Bettina Wilm, Mathias Brust, Patricia Murray, Raphael Levy, Antonius Plagge   +7 more
doaj   +1 more source

Reduced Muscle Force in Dystrophic DMDΔ52 Pigs Is Incompletely Restored by Systemic Transcript Reframing (DMDΔ51–52)

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is a fatal X‐linked disease caused by mutations in the DMD gene, leading to dystrophin deficiency and progressive degeneration of skeletal and cardiac muscles. Pigs lacking DMD exon 52 (DMDΔ52) are a clinically severe model for DMD, mimicking molecular, functional and pathological hallmarks of the ...
Michaela Blasi, Hristiyan Hristov, Jan B. Stöckl, Martin Kraetzl, Sonja Fiedler, Elisabeth Kemter, Mayuko Kurome, Barbara Kessler, Josep M. Cambra, Valeri Zakhartchenko, Maggie C. Walter, Christian Kupatt, Nikolai Klymiuk, Thomas Fröhlich, Andreas Blutke, Michael Stirm, Florian Jaudas, Eckhard Wolf   +17 more
wiley   +1 more source

Immune cell imaging using multi-spectral optoacoustic tomography.

, 2014
Multispectral optoacoustic tomography (MSOT) offers the potential to image in high-resolution cells tagged with optical labels. In contrast to single wavelength imaging, multispectral excitation and spectral unmixing can differentiate labeled moieties ...
Tzoumas, S., Klemm, U., Nunes, A., Schaefer, K., Zaremba, A., Ntziachristos, V.   +5 more
core   +2 more sources

siRNA liposome-gold nanorod vectors for multispectral optoacoustic tomography theranostics. [PDF]

, 2014
Therapeutic applications of gene silencing using siRNA have seen increasing interest over the past decade. The optimization of the delivery and biodistribution of siRNA using liposome-gold nanorod (AuNRs) nanoscale carriers can greatly benefit from adept
Bézière, N., Kostarelos, Kostas, Taruttis, A., Nunes, A., Jasim, Dhifaf, Antonio Nunes, Kostarelos, K., Kostas Kostarelos, Dhifaf A Jasim, Nicolas Beziere, Taruttis, Adrian, Jasim, D.A., Nunes, Antonio, Ntziachristos, V., Ntziachristos, Vasilis, Lozano, Neus, Adrian Taruttis, Lozano, N., Neus Lozano, Herzog, E., Vasilis Ntziachristos, Herzog, Eva, Beziere, Nicolas, Eva Herzog, Taruttis, Adrian;Lozano, Neus;Nunes, Antonio;Jasim, Dhifaf A;Beziere, Nicolas;Herzog, Eva;Kostarelos, Kostas;Ntziachristos, Vasilis   +24 more
core   +2 more sources

Photoacoustic integrated multimodal imaging for breast cancer diagnosis: A review

VIEW, Volume 6, Issue 5, October 2025.
Breast cancer is a complex and challenging to diagnose. This study highlights how combining photoacoustic imaging with traditional techniques like mammography, histopathology, ultrasound, MRI, CT, and artificial intelligence can improve diagnosis, tumor classification, and managing.
Shimul Biswas, Diya Pratish Chohan, Jackson Rodrigues, Ameera K, Stanley Mathew, Krishna Kishore Mahato   +5 more
wiley   +1 more source

Unnatural Triggers Converted From Tetrazine‐Attached Sialic Acid for Activation of Optoacoustic Imaging‐Guided Cancer Theranostics

Angewandte Chemie, Volume 137, Issue 26, June 24, 2025.
Tetrazine precursors (SiaTz) based on a nonO‐acetylated sialic acid scaffold are rationally designed and synthesized, which can be efficiently converted into unnatural tetrazine (Tz) triggers on cancer cell surfaces via metabolic glycoengineering. These Tz triggers activate theranostic agents for multispectral optoacoustic tomographic (MSOT) imaging ...
Yinglong Wu, Lihe Sun, Xiaodong Zhang, Wenbin Zhong, Xiaokai Chen, Shihuai Wang, Yun Chen, Dongdong Wang, Ting He, Hongzhong Chen, Jingjing Guo, Fang Zeng, Menghuan Li, Zhong Luo, Shuizhu Wu, Yanli Zhao   +15 more
wiley   +1 more source

Application of multispectral optoacoustic tomography for lower limb musculoskeletal sports injuries in adults

Photoacoustics
Compositional changes in relation to musculoskeletal injuries are difficult to measure non-invasively. This study aims to use non-invasive label-free imaging with Multispectral Optoacoustic Tomography (MSOT) to evaluate compositional changes with injury.
Rene B. Svensson, Anne-Sofie Agergaard, Thomas Sardella, Charlène Reichl, Mikkel H. Hjortshoej, Monika L. Bayer, Rikke Hoeffner, Christian Couppé, Michael Kjaer, S. Peter Magnusson   +9 more
doaj   +1 more source