Results 61 to 70 of about 668,130 (171)
In Vivo Immunoscoring Technique to Monitor Anti‐CD47 Immunotherapy Efficacy in Triple‐Negative Breast Cancer [PDF]
Intravital imaging using MCP1‐FITC and dextran‐AF680 assesses macrophage targeting and polarization in murine 4T1 tumor models. Visualization of M1‐like and M2‐like macrophages and M1/M2 ratio quantification support evaluation of anti‐CD47 immunotherapy, highlighting the potential of macrophage‐targeted imaging for patient stratification and treatment ...
Yang M +6 more
europepmc +2 more sources
ABSTRACT Surface‐enhanced Raman scattering (SERS) has emerged as a highly sensitive and specific technique for tumor imaging, owing to its narrow spectral features, resistance to photobleaching, and capability for multiplexed detection. However, its clinical translation remains limited by poor tissue penetration and the absence of intrinsic anatomical ...
Xinyu Miao +7 more
wiley +1 more source
Breast cancer is a complex tumor type involving many biological processes. Most chemotherapeutic agents exert their antitumoral effects by rapid induction of apoptosis.
Angelos Karlas +4 more
doaj +1 more source
ABSTRACT Background Late‐onset Pompe disease (LOPD) is a progressive metabolic myopathy characterised by lysosomal glycogen accumulation and leading to secondary disruptions in autophagy and cellular energy metabolism. While enzyme replacement therapy (ERT) has improved outcomes, early detection remains critical, because irreversible muscle damage ...
Alice De Lorenzo +11 more
wiley +1 more source
Fluorescent proteins: A journey from the cell to extreme environments in material science
Applications of proteins and microorganisms as tools or effectors in material science. Abstract This review presents the progression from the use of fluorescent proteins (FPs) and chromoproteins as bioimaging labels and sensors to the strategic engineering of their properties for robust functionality in synthetic and non‐biological environments ...
Bianca Menchicchi +3 more
wiley +1 more source
Fluorescent protein imaging with multispectral optoacoustic tomography.
In this work, we have developed a selective-plane illumination multispectral optoacoustic tomography (MSOT) technique for high-resolution whole-body visualization of intact optically diffusive organisms whose sizes may vary from sub-millimeter up to a ...
Ma, R. +5 more
core +1 more source
Multiparametric optimization of multispectral optoacoustic tomography for deep tissue imaging.
Over the last decade fluorescent reporter technologies (both fluorescent probes and proteins) have become a very powerful imaging tool in everyday biomedical research.
Deliolanis, N.C. +6 more
core +1 more source
Norepinephrine (NE), the primary neurotransmitter of locus coeruleus projections, plays a crucial role in regulating arousal, emotion, memory, and stress responses. Its dysregulation is closely associated with various neurological disorders such as depression, Parkinson’s disease, and epilepsy.
Rufei Ma, Zhao Wang, Sohini Basu Roy
wiley +1 more source
Teachability of multispectral optoacoustic tomography. [PDF]
To date, the appropriate training required for the reproducible operation of multispectral optoacoustic tomography (MSOT) is poorly discussed. Therefore, the aim of this study was to assess the teachability of MSOT imaging.
core +3 more sources
Currently, imaging technologies that enable dermsurgeons to visualize non-melanoma skin cancers (NMSC) in vivo preoperatively are lacking, resulting in excessive or incomplete removal.
Amalina Binte Ebrahim Attia +12 more
doaj +1 more source

