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Trends in Colorectal Cancer Screening in US Adults Aged 45 to 49 Years.
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Multitarget bayes filtering via first-order multitarget moments
IEEE Transactions on Aerospace and Electronic Systems, 2003The theoretically optimal approach to multisensor-multitarget detection, tracking, and identification is a suitable generalization of the recursive Bayes nonlinear filter. Even in single-target problems, this optimal filter is so computationally challenging that it must usually be approximated. Consequently, multitarget Bayes filtering will never be of
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Multitarget Cardiovascular Drugs
Current Medicinal Chemistry, 2011Cardiovascular disease is the number one cause of death globally. Design of cardiovascular drugs based on new paradigms is therefore a prominent goal of medicinal chemistry. Designed multiple ligands, targeting two or more proteins involved in pathogenesis of disease have become a viable concept in drug discovery.
U, Trstenjak, D, Kikelj
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Pemetrexed: A multitargeted antifolate
Clinical Therapeutics, 2005The US Food and Drug Administration approved pemetrexed in February 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin in patients with unresectable disease or for whom curative surgery is not an option. Pemetrexed is the first agent approved for the treatment of MPM.
Kristan D, Rollins, Celeste, Lindley
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Multitarget Antithrombotic Drugs
Current Topics in Medicinal Chemistry, 2011Thromboembolic disorders are still the leading causes of morbidity and mortality in developed societies. Therefore, prophylaxis and treatment of arterial and venous thrombosis are among the main therapeutic challenges nowadays. Simultaneous action on several targets involved in pathology of thrombosis offers potential advantages compared to existing ...
Miloš, Ilić +2 more
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Interval-scaling for multitarget localization
2012 9th Workshop on Positioning, Navigation and Communication, 2012In this paper we illustrate the potential of the generic I-SCAL framework for localization. Much like algebraic Multidimensional Scaling, which was originally utilized in other fields of science until it was identified as suitable for localization, I-SCAL is a SMACOF optimization-based generic framework which, to the best of our knowledge is here, for ...
Jani Saloranta +2 more
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Multitarget range-azimuth tracker
IEEE Transactions on Aerospace and Electronic Systems, 2015We focus on the design of a Kalman filter-based algorithm to track multiple targets in range and azimuth. The detection stage implements a multitarget strategy aimed at collecting and eventually processing all target measurements. Existing tracks are updated using a joint probabilistic data association (JPDA) algorithm to handle the data association ...
BANDIERA, Francesco +2 more
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Multitargeted Treatment of Cancer Cachexia
Critical Reviews™ in Oncogenesis, 2012Cancer cachexia is defined as a multifactorial syndrome characterized by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutritional support and leads to progressive functional impairment. The prominent clinical feature of cachexia is weight loss in adults. Anorexia, inflammation,
MADEDDU, CLELIA +2 more
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