Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Design of multivariable feedback control systems via spectral assignment [PDF]
The applicability of spectral assignment techniques to the design of multivariable feedback control systems was investigated. A fractional representation design procedure for unstable plants is presented and illustrated with an example.
Marefat, M., Mielke, R. R., Tung, L. J.
core +4 more sources
F100 multivariable control synthesis program: Evaluation of a multivariable control using a real-time engine simulation [PDF]
The design, evaluation, and testing of a practical, multivariable, linear quadratic regulator control for the F100 turbofan engine were accomplished. NASA evaluation of the multivariable control logic and implementation are covered.
Cwynar, D. S. +3 more
core +1 more source
Control of sideslip and yaw rate in 4-wheel steering car using partial decoupling and individual channel design [PDF]
, 2003 This paper presents a new steering control structure for cars equipped with 4-wheel steering. This control structure is based on a simplified linear model of the lateral dynamics of such cars and aims to decouple the control of sideslip from the control ...
Leith, D.J. +2 more
core +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Dead-time compensation in three-phase grid-tied inverters using LQG multivariable control. [PDF]
Sci Rep, 2023 Mazaheri A, Barati F, Ghavipanjeh F.
europepmc +1 more source
F100 multivariable control synthesis program: A review of full scale engine altitude tests [PDF]
The benefits of linear quadratic regulator synthesis methods in designing a multivariable engine control capable of operating an engine throughout its flight envelope were demonstrated.
Lehtinen, B., Soeder, J. F.
core +1 more source
Robust control of a bimorph mirror for adaptive optics system [PDF]
, 2008 We apply robust control technics to an adaptive optics system including a dynamic model of the deformable mirror. The dynamic model of the mirror is a modification of the usual plate equation. We propose also a state-space approach to model the turbulent
Arzelier, Denis +3 more
core +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source
Hookworm Infection and Environmental Factors in Mbeya Region, Tanzania: A Cross-sectional, Population-based study. [PDF]
, 2013 Hookworm disease is one of the most common infections and cause of a high disease burden in the tropics and subtropics. Remotely sensed ecological data and model-based geostatistics have been used recently to identify areas in need for hookworm control ...
A Huete +47 more
core +4 more sources