Is outcome observed in performance of clinical tests associated with patient-reported outcome measures after patellofemoral pain treatment? Secondary analysis of data from a randomized clinical trial. [PDF]
Machado EM +4 more
europepmc +1 more source
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang +19 more
wiley +1 more source
Psychometric evaluation of a four-item scale derived from the PHQ-9 and GAD-7 among community adults based on multivariate generalizability theory and item response theory. [PDF]
Cheng N +10 more
europepmc +1 more source
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li +6 more
wiley +1 more source
Dual diagnosis of acidification dynamics in Amazonian urban lakes: multivariate analysis and calcite saturation index for status and vulnerability assessment. [PDF]
Noriega C +8 more
europepmc +1 more source
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li +13 more
wiley +1 more source
Fedorov algorithm-optimized chemometric spectrophotometry for cefepime-tazobactam microanalysis in plasma and pharmaceuticals with integrated MA and NQS sustainability assessment. [PDF]
Gad AG +4 more
europepmc +1 more source
Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates
Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao +4 more
wiley +1 more source
The Aggregated Latent Profile Index: Measuring Person Profile Differentiation Within a Bootstrap-Validated Latent Profile Space. [PDF]
Kim SK.
europepmc +1 more source
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang +10 more
wiley +1 more source

