Results 191 to 200 of about 299,199 (234)

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

Garbage in, garbage out: stringent quality control of behavioral data boosts signal in brain-behavior associations. [PDF]

Cereb Cortex
Elsayed M, Deng WQ, Belisario KL, MacKillop J.   +3 more
europepmc   +1 more source

A general framework for using two-stage meta-analysis with individual participant data to predict individualized treatment effects

Mainetti M, Chalkou K, Philipona FL, Schwarzer G, Salanti G, Efthimiou O.   +5 more
europepmc   +1 more source

Seasonal Trace Element Contamination and Health Risk Assessment of the Mediterranean Limpet (<i>Patella caerulea</i>) from the Southern Black Sea. [PDF]

Life (Basel)
Gökkurt Baki O.
europepmc   +1 more source

Cannabinoid receptor expression profiling in lymphocyte subsets reveals clinically relevant immune patterns in SLE. [PDF]

Front Immunol
Rosero AM, Rios-Serna LJ, Cañas CA.
europepmc   +1 more source

Methodology for Selecting Stable UAV-Based Vegetation Indices for Prediction of Agronomic Variables in Maize Using a Multispectral Sensor. [PDF]

Plants (Basel)
Lima CDS, Soares AJT, Nogueira BDS, Vian AL, Carvalho IR, Bredemeier C.   +5 more
europepmc   +1 more source

Integrated molecular and phenotypic analysis of onion (<i>Allium cepa</i> L.) germplasm reveals limited correspondence between genetic structure and phenotypic traits. [PDF]

Front Plant Sci
Sinkovič L, Tavakoli Hasanaklou H, Karče Poljanšek N, Šuštar Vozlič J, Pipan B.   +4 more
europepmc   +1 more source

Electronic Nose-Based Exhaled Volatile Organic Compound Pattern Recognition and Multivariate Signal Analysis for Discriminating Idiopathic Pulmonary Fibrosis from Autoimmune Usual Interstitial Pneumonia. [PDF]

Sensors (Basel)
Di Marco M, Marinelli A, Quaranta VN, Portacci A, Boniello E, Labate L, Caringella A, Violante A, Carpagnano GE, Dragonieri S.   +9 more
europepmc   +1 more source